DENİZ KAVGACI HALİME HELİN YILMAZ TESTICULAR TUMORS DENİZ KAVGACI HALİME HELİN YILMAZ
TNM STAGING American Joint Committee on Cancer (AJCC) T the extent of spread of the primary tumor to the tissues next to the testicle N number of lymph nodes affected M metastasis +/- S indicates the serum level of tumor markers (specific for certain types of testicular cancers)
STAGING OF TESTICULAR CANCER Stage I: tumor confined to the testis Stage II: spread to regional lymph nodes IIA: <2 cm in size or < 6 positive nodes IIB: 2-5 cm in size or > 6 positive nodes IIC: large and bulky abdominal mass, usually > 5-10 cm Stage III: spread beyond retroperitoneal nodes or above diaphragm or visceral disease Stage IV: hematogenous spread
TREATMENT OF SEMINOMAS Low grade (stage I and IIA) Radical inguinal orchiectomy Surveillance RT or single agent carboplatin High grade (stage >IIA) RPLND RT and/or CT
NON-SEMINOMATOUS GERM CELL TUMOR Management of men with NSGCT stage I depends on the presence of factors that present an increased risk of relapse: - Lymphovascular invasion - Predominance of an embryonal carcinoma component - A T3 or T4 primary tumor
NSGCT TREATMENT
REFERANCES www.uptodate.com www.medscape.com www.cancer.net THANK YOU…