Relationship of oxygenation, as reflected in the ratio of the arterial and alveolar oxygen tensions (a/A ratio), to the mean airway pressure (mPaw) applied.

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Relationship of oxygenation, as reflected in the ratio of the arterial and alveolar oxygen tensions (a/A ratio), to the mean airway pressure (mPaw) applied during HFOV, at constant tidal volume and frequency, in an infant with respiratory distress syndrome. No circulatory instability occurred over the entire range of mean pressures. CO2 elimination could be achieved equally well using a high FIO2 and a low mPaw or a low FIO2 and a higher mPaw. A choice of operating conditions had to be made. (From Marchak, et al. Treatment of RDS by high-frequency oscillatory ventilation: a preliminary report. J Pediatr. 1981;99:287–292. Reproduced with permission of Mosby, Inc.) Source: Chapter 19. High-Frequency Ventilation, Principles and Practice of Mechanical Ventilation, 3e Citation: Tobin MJ. Principles and Practice of Mechanical Ventilation, 3e; 2013 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/tobi3/tobi3_c019f002.png&sec=41695676&BookID=520&ChapterSecID=41692260&imagename= Accessed: December 25, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved