POLG1 mutations should be considered in teenagers and young adults reporting episodic visual symptoms with migraine-like headaches and sudden-onset intractable.

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POLG1 mutations should be considered in teenagers and young adults reporting episodic visual symptoms with migraine-like headaches and sudden-onset intractable seizures. Due to the risk of liver failure, valproic acid should be avoided when treating patients with POLG1 phenotypes.296,299 Source: Focal Epilepsy, Atlas of Pediatric EEG Citation: Laoprasert P. Atlas of Pediatric EEG; 2011 Available at: http://neurology.mhmedical.com/DownloadImage.aspx?image=/data/books/1042/lao001_fig_09-161.gif&sec=59080228&BookID=1042&ChapterSecID=59078731&imagename= Accessed: December 25, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved