From: Natural Bioadhesive Biodegradable Nanoparticle-Based Topical Ophthalmic Formulations for Management of Glaucoma Trans. Vis. Sci. Tech.. 2015;4(3):12.

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From: Natural Bioadhesive Biodegradable Nanoparticle-Based Topical Ophthalmic Formulations for Management of Glaucoma Trans. Vis. Sci. Tech.. 2015;4(3):12. doi:10.1167/tvst.4.3.12 Figure Legend: Twenty-four hour IOP profiles (a and b) after a single application of ophthalmic formulation containing brimonidine-loaded NPs in one eye or (c and d) untreated control eye of mice. IOP profiles of the treated eyes of mice with spontaneously elevated IOP are shown in panel a while mice with normal IOP are shown in panel b. IOP profiles of the untreated control eyes of mice with spontaneously elevated IOP and mice with normal IOP are shown in c and d, respectively. Data are presented as mean ± SEM; n = 5. Date of download: 12/25/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.