Hypogonadism in aging men

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Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Presentation transcript:

Hypogonadism in aging men Hypogonadism in aging men. Bar height indicates the percentage of men in each 10-year interval, from the third to the ninth decades, with at least one testosterone (T) value in the hypogonadal range, by the criteria of total T <11.3 nmol/L (325 ng/dL) [shaded bars], or T/SHBG (free T index) <0.153 nmol/nmol (striped bars). Numbers above each pair of bars indicate the number of men studied in the corresponding decade. The fraction of men who are hypogonadal increases progressively after age 50 by either criterion. More men are hypogonadal by free T index than by total T after age 50, and there seems to be a progressively greater difference, with increasing age, between the two criteria (T, testosterone; SHBG, sex hormone–binding globulin; T/SHBG, free T index). (Reproduced, with permission, from Harman SM, et al. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. J Clin Endocrinol Metab. 2001;86:724. Copyright 2001 by The Endocrine Society.) Source: Chapter 23. Geriatric Endocrinology, Greenspan’s Basic & Clinical Endocrinology, 9e Citation: Gardner DG, Shoback D. Greenspan’s Basic & Clinical Endocrinology, 9e; 2011 Available at: https://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/gard9/gard9_c023f019.gif&sec=39750907&BookID=380&ChapterSecID=39744063&imagename= Accessed: December 25, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved