Copyright © 2017 McGraw-Hill Education. All rights reserved Relationship between onset, duration, and spread of sensory anesthesia and onset, duration, and frequency of motor block produced by bupivacaine when employed as either a 0.5% or a 0.75% solution for intrathecal use. [Reprinted from Covino BG. Pharmacology of local anesthetic agents. In: Rogers MC, Tinker JH, Covino BG, et al, eds. Principles and Practice of Anesthesiology, Vol. 2. St. Louis, MO: Mosby Year Book; 1993:1240, with permission from Elsevier.] Source: Chapter 45. Pharmacology of Local Anesthetics*, Anesthesiology, 2e Citation: Longnecker DE, Brown DL, Newman MF, Zapol WM. Anesthesiology, 2e; 2012 Available at: https://accessanesthesiology.mhmedical.com/DownloadImage.aspx?image=/data/books/long2/long2_c045f016.png&sec=40124421&BookID=490&ChapterSecID=40114732&imagename= Accessed: December 25, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved