From: Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork Invest. Ophthalmol. Vis. Sci.. 2017;58(3):1811-1823.

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Presentation transcript:

From: Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork Invest. Ophthalmol. Vis. Sci.. 2017;58(3):1811-1823. doi:10.1167/iovs.16-21331 Figure Legend: TLR4 is expressed in the human and mouse TM. Cross sections of eight individual human eyes were labeled with a TLR4-specific antibody. (A) No primary antibody control. (B) TLR4 expression in the human TM (TM, trabecular meshwork; SC, Schlemm's canal; AC, anterior chamber; I, iris). (C) RNA was isolated from primary human TM cell strains and a human transformed TM cell line, GTM3. Using primers specific to human TLR4, RT-PCR was performed. TLR4 is expressed in human TM cells. (D) The TM ring from mice was carefully dissected and RNA isolated. Using primers specific to mouse Tlr4, RT-PCR was performed. Tlr4 is expressed in the TM ring of C3H/HeJ, C57BL/6J, and A/J mice. Date of download: 12/25/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.