Figure 2 In situ hybridization for rhinovirus type 14 (rhinovirus-14) in maxillary sinus biopsy specimens. A, Detection of rhinovirus-14, antisense probe,

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Figure 2 In situ hybridization for rhinovirus type 14 (rhinovirus-14) in maxillary sinus biopsy specimens. A, Detection of rhinovirus-14, antisense probe, in a maxillary sinus biopsy specimen obtained from the patient with maxillary sinusitis. Positive hybridization signal is visible as cytoplasmic brown reactivity in respiratory epithelial cells. B, Adjacent section from the same biopsy specimen, probed with rhinovirus-14 sense probe, demonstrates no hybridization signal. C, Rhinovirus-14 antisense-negative maxillary sinus biopsy specimen obtained from another patient with acute sinusitis. D, Lack of rhinovirus-14 reactivity in a maxillary sinus biopsy specimen obtained from the maxillary sinus of an uninfected patient during decompression surgery. Bar = 10 µm. From: Rhinovirus RNA in the Maxillary Sinus Epithelium of Adult Patients with Acute Sinusitis Clin Infect Dis. 2001;33(6):909-911. doi:10.1086/322678 Clin Infect Dis | © 2001 by the Infectious Diseases Society of America 1