Schematic diagram showing arrangement of thick and thin filaments within the sarcomere. Thick filaments contain myosin, myosin-binding protein C, and titin.

Slides:

Advertisements

Similar presentations

Muscle cells possess contractile filaments containing actin and myosin

Advertisements

Types of Muscle, structure and Function

Structure of Skeletal Muscle Presentation by: Angela Holloman.

Muscle Specialized for: Types:.

Sliding Filament Theory

Fig Myofibrils are surrounded by calcium- containing sarcoplasmic reticulum.

Sliding Filament Theory How do muscles work…... Muscle Cell Structure n Muscles are broken into smaller muscle fibers n muscle fibers are broken into.

Week 1 Click images for hyperlinks!. What is a muscle? Muscles are organs made of muscular and connective tissues, which make up the Muscular System They.

CONTRACTION OF SKELETLAL MUSCLE: SLIDING FILAMENT THEORY

Copyright © 2006 Lippincott Williams & Wilkins. Muscular System Chapter 11 Part 2.

Contraction of Skeletal Muscles. Physiologic Anatomy of Skeletal Muscle.

Muscles n Skeletal muscle organization and how it contracts.

Muscular system SKELETAL MUSCLE Skeletal muscle is made up of hundreds of muscle fibers –Fibers consists of threadlike myofibrils –Myofibrils composed.

Sliding Filament Theory

The Steps of the Sliding Filament Theory

Warm-Up 4/8/15 1.What is an autoimmune disorder? 2.What how are LEMS and MG similar? 3.How are LEMS and MG different? Test - Tuesday.

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Neuromuscular Junction Figure 9.7 (a-c)

STRUCTURE OF SKELETAL MUSCLE

Myosin Myosin is a protein molecule found in the thick filaments. Myosin is a protein molecule found in the thick filaments.

OBJECTIVES At the end of this lecture the student should be able to: Define different types of muscles Enumerate cellular organization of human skeletal.

7.2 Microscopic Anatomy and Contraction of Skeletal Muscle

 Name the following movements: ◦ Increasing angle of joint (ex. Straightening arm) ◦ Moving around longitudinal axis: ◦ Moving a limb away from midline.

MUSCLE CONTRACTION. Microscopic Anatomy of Skeletal Muscle Sarcomere Contractile unit of a muscle fiber Figure 6.3b.

Muscle Cells & Muscle Fiber Contractions

Cardiac Muscle Involuntary –heart only Contracts & relaxes continuously throughout life –Contracts without nervous stimulation! –A piece of cardiac muscle.

IN CLASS NOTES = STEPS OF A MUSCLE CONTRACTION. STEP 1 Calcium ions present Ca+ binds to troponin which makes tropomyosin move out of way for myosin head.

Pathophysiology and Management of Hypercyanotic or TET spells Leanne Meakins RN, MN, NP Congenital Cardiac Symposium 25 October 2013.

David Sadava H. Craig Heller Gordon H. Orians William K. Purves David M. Hillis Biologia.blu C – Il corpo umano Musculoskeletal System.

Interaction of thick & thin filaments __________________ –_____________________________________ _____________________________________ –_____________________________________.

Sliding Filament.

Synapse – The site of connection between a neuron and a cell. Neurotransmitter – A chemical released at the neuron’s synapse that communicates with the.

Muscles & Motor Locomotion Why Do We Need All That ATP?

Three types of muscle Skeletal – attached to bone

The Sliding Filament Theory

Muscular System Notes. Microscopic Muscle Anatomy  Myfibrils  About 1-2 micrometers in diameter  Length of a muscle fiber  Composed of multiple myofilaments.

Figure 10.6 Levels of Functional Organization in Skeletal Muscle Fiber

Ch 36 Musculoskeletal System AP lecture Three vertebrate muscles Skeletal – A.k.a striated – Voluntary movements.

Lecture #21 Date ____ n Chapter 49 ~ Sensory and Motor Mechanisms.

Molecular Basis of Muscle Contraction Standard 9 h. Students know the cellular and molecular basis of muscle ocntraction,including the roles of actin,

Muscle voluntary, striated involuntary, striated auto-rhythmic involuntary, non-striated evolved first multi-nucleated digestive system arteries, veins.

Muscle contraction Public domain image. Muscle has two purposes Generate motion Generate force.

AP Biology Thick filaments: myosin  Protein  myosin molecule  long protein with globular head bundle of myosin proteins: globular heads aligned.

How do muscle cells contract ?. What is the structure of a muscle fiber ? The sarcolemma, or plasma membrane contains invaginations called T (transverse)

MUSCLES LECTURE 14 CHAPTER 12 MECHANISMS OF CONTRACTION.

Muscle Types and Their Characteristics. Skeletal Muscle Anatomy.

HOW DO MUSCLES CONTRACT?

Muscle Fiber Contraction

Muscle contraction.

Sliding Filament Theory

The Ca2+ fluxes and key structures involved in cardiac excitation-contraction coupling. The arrows denote the direction of Ca2+ fluxes. The thickness of.

A practical approach to differentiating tachyarrhythmias

Excitation–Contraction Coupling

Nerve MUSCLE PHYSIOLOGY

Skeletal muscle sarcomere

Arrangement of filaments in striated muscle. (A) Extended

A practical approach to differentiating tachyarrhythmias

Schematic diagram showing arrangement of thick and thin filaments within the sarcomere. Thick filaments contain myosin, myosin-binding protein C, and titin.

Critical pulmonary stenosis

A skeletal muscle is composed of a variety of tissues

Prayer Homework Attendance.

Muscle Contraction.

SURVEY OF BIOCHEMISTRY Protein Function

The Genetic Basis for Cardiomyopathy

Vertebrate Anatomy – Ch. 9 AP Biology – Ch. 49

Microscopic Anatomy of Skeletal Muscle Fibers

Muscle and Muscle Contraction

Between Disease-Causing and an Innocent Bystander: The Role of Titin as a Modifier in Hypertrophic Cardiomyopathy Brenda Gerull, MD Canadian Journal.

Genetic Pathogenesis of Hypertrophic and Dilated Cardiomyopathy

Regulation of Contraction by the Thick Filaments in Skeletal Muscle

Contraction II Department of Biology, WCU.

Presentation transcript:

Schematic diagram showing arrangement of thick and thin filaments within the sarcomere. Thick filaments contain myosin, myosin-binding protein C, and titin. The tails of the myosin heavy chains are woven together to form the thick filament. The globular head projects outward to form cross bridges. The thin filaments include actin (which forms the backbone of the thin filament), the troponins, and tropomyosin. Tropomyosin binds to troponin T at multiple sites along the major groove of the actin filament and inhibits actin-myosin interaction. Troponin T binds the troponin complex to tropomyosin, troponin I inhibits interactions between actin and myosin, and troponin C binds calcium. The sarcomere, which lies between two Z-discs, is anchored by interactions between titin and actin with Z-disc proteins, including LIM domain-binding protein 3 (cipher/ZASP), α-actinin, cardiac LIM domain protein (MLP), and telethonin. Adapted from Mahony L. Development of myocardial structure and function. In: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, eds. Moss and Adams’ Heart Disease in Infants, Children and Adolescents, 7th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2008:577. Source: Myocyte Contraction and Relaxation, Neonatal Cardiology, 3e Citation: Artman M, Mahony L, Teitel DF. Neonatal Cardiology, 3e; 2017 Available at: http://accesspediatrics.mhmedical.com/DownloadImage.aspx?image=/data/books/2045/neocard3_ch2_f002.png&sec=154264333&BookID=2045&ChapterSecID=154264304&imagename= Accessed: December 26, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved