Diagnostic Accuracy of Inflammatory Markers for Diagnosing Occupational Asthma  Geneviève Racine, Roberto Castano, MD, PhD, André Cartier, MD, Catherine.

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Presentation transcript:

Diagnostic Accuracy of Inflammatory Markers for Diagnosing Occupational Asthma  Geneviève Racine, Roberto Castano, MD, PhD, André Cartier, MD, Catherine Lemiere, MD, MSc  The Journal of Allergy and Clinical Immunology: In Practice  Volume 5, Issue 5, Pages 1371-1377.e1 (September 2017) DOI: 10.1016/j.jaip.2017.02.001 Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 1 Receiver operating characteristic curves evaluating the effectiveness of PC20, blood eosinophilia, and sputum eosinophilia before SICs for diagnosing occupational asthma (n = 591). PC20, Concentration of methacholine inducing a 20% fall in forced expiratory volume in 1 second; SIC, specific inhalation challenge. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 1371-1377.e1DOI: (10.1016/j.jaip.2017.02.001) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 2 Receiver operating characteristic curves evaluating the effectiveness of the change in PC20 and sputum eosinophilia after the SICs for diagnosing occupational asthma (n = 477). PC20, Concentration of methacholine inducing a 20% fall in forced expiratory volume in 1 second; SIC, specific inhalation challenge. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 1371-1377.e1DOI: (10.1016/j.jaip.2017.02.001) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 3 Receiver operating characteristic curves evaluating the effectiveness of the change in PC20, blood eosinophilia, and sputum eosinophilia after the SICs for diagnosing occupational asthma (n = 77). PC20, Concentration of methacholine inducing a 20% fall in forced expiratory volume in 1 second; SIC, specific inhalation challenge. The Journal of Allergy and Clinical Immunology: In Practice 2017 5, 1371-1377.e1DOI: (10.1016/j.jaip.2017.02.001) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions