C. A peripheral nerve fiber is myelinated by a Schwann cell in several stages. In stage 1 the Schwann cell surrounds the axon. In stage 2 the outer aspects.

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C. A peripheral nerve fiber is myelinated by a Schwann cell in several stages. In stage 1 the Schwann cell surrounds the axon. In stage 2 the outer aspects of the plasma membrane have become tightly apposed in one area. This membrane fusion reflects early myelin membrane formation. In stage 3 several layers of myelin have formed because of continued rotation of the Schwann cell cytoplasm around the axon. In stage 4 a mature myelin sheath has formed; much of the Schwann cell cytoplasm has been squeezed out of the innermost loop. (Adapted, with permission, from Williams et al. 1989.) Source: The Cells of the Nervous System, Principles of Neural Science, Fifth Editon Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available at: http://neurology.mhmedical.com/DownloadImage.aspx?image=/data/Books/1049/kan_ch4_f013.png&sec=59140206&BookID=1049&ChapterSecID=59138626&imagename= Accessed: December 27, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved