Volume 136, Issue 2, Pages 505-512 (February 2009) Predictive Factors for Early HBeAg Seroconversion in Acute Exacerbation of Patients With HBeAg-Positive Chronic Hepatitis B  Hyoung Su Kim, Ha Jung Kim, Woon Geon Shin, Kyung Ho Kim, Jin Heon Lee, Hak Yang Kim, Myoung Kuk Jang  Gastroenterology  Volume 136, Issue 2, Pages 505-512 (February 2009) DOI: 10.1053/j.gastro.2008.10.089 Copyright © 2009 AGA Institute Terms and Conditions

Figure 1 Patient flow diagram. Gastroenterology 2009 136, 505-512DOI: (10.1053/j.gastro.2008.10.089) Copyright © 2009 AGA Institute Terms and Conditions

Figure 2 (A) Cumulative occurrence rates of HBeAg seroconversion were 41%, 57%, 65%, and 72% at 1, 3, 5, and 7 years, respectively. (B) Cumulative occurrence rates of HBeAg reversion were 14%, 42%, 52%, and 67% at 1, 3, 5, and 7 years, respectively. Gastroenterology 2009 136, 505-512DOI: (10.1053/j.gastro.2008.10.089) Copyright © 2009 AGA Institute Terms and Conditions

Figure 3 Cumulative occurrence rates of active hepatitis at 1, 3, 5, and 7 years were 22%, 49%, 53%, and 60% in the early HBeAg seroconversion group and 29%, 68%, 80%, and 87% in the nonearly HBeAg seroconversion group, respectively. The median time during which patients presented active hepatitis tended to be longer in the early HBeAg seroconversion group than in the nonearly HBeAg seroconversion group (55 months [range, 6–86 months] vs 24 months [range, 5–96 months]; P = .08). Gastroenterology 2009 136, 505-512DOI: (10.1053/j.gastro.2008.10.089) Copyright © 2009 AGA Institute Terms and Conditions