Potential effects of 10kg wt loss in Type 2 diabetes

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Presentation transcript:

Potential effects of 10kg wt loss in Type 2 diabetes Mortality >20% fall >30% fall in DM related death >40% fall in obesity related death BP Sys BP 10mmHg, Dia 20mmHg Glucose 50% fall in Fasting glucose Lipid Profile 10% fall in Total Cholesterol 15% fall LDL-C 30% Triglyceride 8% Rise in HDL-C Magnitude of expected benefit Br J Diab Vasc Dis 11(1) Jan 2011

UKPDS -What happens after 18 years UKPDS -What happens after 18 years ? Remember: No difference in Hba1c betweeen groups after initial 8 years Favours early glucose lowering