Product specification

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Presentation transcript:

Product specification Software specification Main - exclusive features Overview Parameters Reagents & Controls Rack loader & sample principles CDR Measurement principles Customer maintenance Environmental protection

Compact bench top system Overview Compact bench top system No external computer is requested Touch screen Reagent Compartment Processed Tubes Rack Loader 10 racks of 10 tubes Stat Sample Bay

WBC, RBC, HGB, HCT, MCV, MCH, MCHC, RDW, PLT, MPV, PCT, PDW Parameters CBC Mode (12 Parameters) WBC, RBC, HGB, HCT, MCV, MCH, MCHC, RDW, PLT, MPV, PCT, PDW 5 DIFF Mode ( 26 Parameters) LYM, MON, NEU, EOS, BASO (% and #) ALY (Atypical Lymphocytes) (% and #) LIC (Large Immature Cells) (% and #) 80 samples per hour Manual or automatic CBC or DIF (random access)

5 reagents Control bloods : ABX Cleaner ABX Biolyse ABX Basolyse II Reagents & Controls 5 reagents ABX Cleaner ABX Biolyse ABX Basolyse II ABX Eosinofix + ABX Diluent Onboard reagents Bar-coded Waste level sensor Control bloods : Bar-coded Target values uploaded by floppy disk

Sampler capacity : 10 racks of 10 samples Rack loader Sampler capacity : 10 racks of 10 samples XL walk-away autonomy : 1hour 15mn

Automatic mode with end over end mixing Sampling Automatic mode with end over end mixing 30 µl (CBC) 53 µl (CBC+DIFF) Manual (open or close) mode Internal and external barcode reader

CDR = Customized Dilution Ratio CDR - Purpose CDR = Customized Dilution Ratio Purpose : Pushing the limits of linearity without blood manipulation and in a very user friendly way The CDR eliminates manual dilution error and secure the result !

1- Manual selection of the dilution ratio CDR - Operation The end-user can use the CDR in 2 modes : 1- Manual selection of the dilution ratio The end-user can program 3 dilution ratios:

2- Automatic selection of dilution ratio CDR - Operations 2- Automatic selection of dilution ratio CDR are programmed to rerun samples for every “DIL” flag with predefined dilution ratio

Measurement principles RBC/PLT - Impedance HGB - Cyanmethemoglobin or cyanide free WBC - Impedance & optical BASO - Impedance & specific lyse HGB measurement Method Photometry Wavelenght 555 nm Dilution ratio 1/250 Reaction temperature 35°C HCT measurement Method Numeric integration WBC & BASO count Method Impedance Ruby diameter 80 µm Depression of count 200 mb Duration of count 2  6 seconds Dilution ratio 1/200 Reaction temperature 35°C

Measurement principles  1. Cytochemistry Lyses red blood cells Stains nuclei and cytoplasmic granules of leukocytes Fixes the leukocytes in their original state (48 hours post-draw stability) 2. Double hydrodynamic focusing (DHSS) Flow-cytometer with hydrodynamic focusing before and after the aperture    Differentiation Ruby diameter 60µm Diameter of the flow 42µm Injection duration 12 seconds Dilution ratio 1/80 Incubation duration 12 seconds Reaction duration 35°C 3. Impedance method Cell volume (“X” axis) 4. Light absorbance Analysis of the internal structure (“Y” axis”)

Measurement principles The determination of the 5 per differential uses : X -> Cellular volume Y -> Intensity of staining Eosinophils Large Immature Cells Neutrophils Monocytes Lymphocytes Atypical Lymphocytes

General flags RBC and PLT curves “l” and “h” (normal limit) Flags and alarms General flags “l” and “h” (normal limit) “L” and “H” (panic limit) “x” (reject) “!” (suspicion) Pathologic messages RBC and PLT curves

5 per differential matrix Flags and alarms 5 per differential matrix 1- Priority alarms ALY: (Atypical Lymphocytes) Atypical Lymphocytes Plasmocytes, hairy Cells LIC: (Large Immature Cells) Blasts, myelocytes Promyelocytes, Metamyelocytes

5 per differential matrix Flags and alarms 5 per differential matrix 2- Separation alarms Nl: (Neutro-lympho) Hypo-segmented neutrophils Sezary cells, hairy cells Ne: (Neutro-eosino) Hyper-segmented neutrophils Hypo-granular eosinophils Mn: (Mono-neutro) Immature granulocytes, band cells

5 per differential matrix Flags and alarms 5 per differential matrix 3- Zone alarms Rm: (Right-mono) Large monocytes, blasts No: (Noise) Platelet aggregates, NRBCs Lysis resistant RBCs Ln: (Left-neutro) Cellular debris Rn: (Right-neutro) Immature granulocytes Ll, Ll1: (Left-lympho) Platelet aggregates, NRBCs

Only one automatic shut-down per day Customer maintenance Only one automatic shut-down per day Stepper motors replace the old compressor concept -> No noise, no maintenance A double needle replaces the sampling valve concept -> No clogging, no maintenance Liquid valves replace the old pinch valve concept

Environmental protection Liquid waste 32 ml / sample Solid waste 1,83 g / sample

Environmental protection Power Requirements Power supply From 100 V to 240 V (50 HZ to 60 Hz) Power consumption Maximum 230 VA

Product specification Software specification Main - exclusive features System specification Worklist Data processing Validation station

Colour LCD touch screen Windows XP Query mode System Colour LCD touch screen Windows XP Query mode Random access (DIFF or CBC mode) Onboard validation-station Onboard user manuel Real-time management of patient’s report

9 logs for : Maintenance Calibration Controls Errors Data Handling System 9 logs for : Maintenance Calibration Controls Errors Data Handling Patient record Settings Blank cycles Connection

Manual entry or host connection Worklist Manual entry or host connection Easy to set up Real time visualisation Maximum security Demographic data, department... Comment

Automatic validation Automatic validation based on: Flags, Alarms, Limits, Delta check

Building up a patient report (1) Patient report built by selective choice from: Run Re-run Manual entry Pathology level

Product specification Software specification Main - exclusive features

Qualification & quantification of ALY and LIC Main features Qualification & quantification of ALY and LIC Automatic and immediate rerun Real manual open tube and manual close tube Real capillary mode (30 µl for CBC, 53µl for CBC+Diff) Integrated validation station Compact, simple, reliable (no shear valve, no compressor, only one PCB) Automatic shutdown cycle - No customer maintenance Small reagent consumption Low power consumption