Image Challenge Q: What is the diagnosis in this 42-year-old man with bone pain? 1. Hypervitaminosis A 2. Gaucher's disease 3. Multiple myeloma 4. Osteopetrosis.

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Presentation transcript:

Image Challenge Q: What is the diagnosis in this 42-year-old man with bone pain? 1. Hypervitaminosis A 2. Gaucher's disease 3. Multiple myeloma 4. Osteopetrosis 5. Thalassemia minor

Image Challenge Q: What is the diagnosis in this 42-year-old man with bone pain? Answer: Gaucher's disease Bone involvement is common in Gaucher's disease. Flaring of the distal femur, the so-called Erlenmeyerflask deformity, is a classic sign of the disease. Marrow infarctions are also present throughout. Secondary osteoarthritic changes are due to subchondral bony collapse resulting from osteonecrosis.