From: Photic Injury to Cultured RPE Varies Among Individual Cells in Proportion to Their Endogenous Lipofuscin Content as Modulated by Their Melanosome.

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From: Photic Injury to Cultured RPE Varies Among Individual Cells in Proportion to Their Endogenous Lipofuscin Content as Modulated by Their Melanosome Content Invest. Ophthalmol. Vis. Sci.. 2014;55(8):4982-4990. doi:10.1167/iovs.14-14310 Figure Legend: Illustration of the movement of a representative lipofuscin granule at baseline and with sublethal blue light treatment. Bright field micrographs, with overlaid movement tracks, show organelle motility over 3-minute intervals at baseline ([A], track shown in black), then during ([B], track shown in blue) and after ([C], track shown in green) blue light irradiation. (D) Graphical representation of the movement of the lipofuscin granule shown in (A–C). Age of RPE donor: 84 years. Magnification for (A–C): ×600. Date of download: 12/27/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.