Evidence suggesting coronary vasodilation as the principal mechanism in the warm-up phenomenon Kari Ylitalo, MD, PhDa, Matti Niemelä, MDa, Markku Linnaluoto,

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Presentation transcript:

Evidence suggesting coronary vasodilation as the principal mechanism in the warm-up phenomenon Kari Ylitalo, MD, PhDa, Matti Niemelä, MDa, Markku Linnaluoto, McSa, Juhani Valkama, MDa, Kimmo Mattila, MDb, Keijo Peuhkurinen, MD, PhDc American Heart Journal Volume 141, Issue 6, Pages 5A-12A (June 2001) DOI: 10.1067/mhj.2001.115438 Copyright © 2001 Mosby, Inc. Terms and Conditions

Fig. 1 The design of the study. After the first 2 successive exercise tests, patients were randomized to receive either nisoldipine 10 mg twice daily or a placebo for 2 days. On day 2 the coronary angiography was performed. The second pair of successive exercise tests was performed on day 3 at least 2 hours after the last dose of nisoldipine or placebo. American Heart Journal 2001 141, 5A-12ADOI: (10.1067/mhj.2001.115438) Copyright © 2001 Mosby, Inc. Terms and Conditions

Fig. 2 Maximal anginal pain during successive exercise tests. Two asterisks, P < .01; three asterisks, P < .001 versus test 1 on the same day; three pound signs, P < .001 versus test 1 on day 1. ex, Exercise test. American Heart Journal 2001 141, 5A-12ADOI: (10.1067/mhj.2001.115438) Copyright © 2001 Mosby, Inc. Terms and Conditions

Fig. 3 Time to 1-mm ST depression during successive exercise tests. Asterisk, P < .05; three asterisks, P < .001 versus test 1 on the same day; three pound signs, P < .001 versus test 1 on day 1. ex, Exercise test. American Heart Journal 2001 141, 5A-12ADOI: (10.1067/mhj.2001.115438) Copyright © 2001 Mosby, Inc. Terms and Conditions