Effects of PTH and 1,25-dihydroxycholecalciferol on whole body calcium homeostasis. A reduction in plasma calcium stimulates parathyroid hormone secretion.

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Effects of PTH and 1,25-dihydroxycholecalciferol on whole body calcium homeostasis. A reduction in plasma calcium stimulates parathyroid hormone secretion. PTH in turn causes calcium conservation and production of 1,25-dihydroxycholecalciferol in the kidneys, the latter of which increases calcium uptake in the intestine. PTH also releases calcium from the readily exchangeable pool in the bone. All of these actions act to restore normal plasma calcium. (Reproduced with permission from Vander A, Sherman J, Lueiano D: Vander’s Human Physiology, 8th ed. McGraw-Hill, 2001.) Source: Hormonal Control of Calcium & Phosphate Metabolism & the Physiology of Bone, Ganong's Medical Physiology Examination & Board Review Citation: Barrett KE, Barman SM, Boitano S, Reckelhoff JF. Ganong's Medical Physiology Examination & Board Review; 2017 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/2139/barganong_ch21_f002-1.png&sec=160313047&BookID=2139&ChapterSecID=160313018&imagename= Accessed: December 28, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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