Synthesis and activation of vitamin D (cholecalciferol)

Slides:



Advertisements
Similar presentations
Hypothyroidism. A. Primary hypothyroidism results from failure of the thyroid gland and causes low plasma thyroid hormone levels. There is loss of negative.
Advertisements

CMS-1500 Outpatient Medical Service Claim Form
Colonic adenocarcinoma metastases to the liver
The Physiology and Pathophysiology of Vitamin D
Actions of Leukotriene Antagonists and Corticosteroids
A. Formation of the Platelet Plug
Vitamin D3 Presented by John Lear.
Formation of vitamin C radical by reduction of the vitamin E radical
Proopiomelanocortin (POMC) processing
Nine patterns of inflammatory skin disease. (See also Table 8–1.)
Modification of the trade-off hypothesis of Slatopolsky and Bricker as it relates to the adaptation of the body to decreased functional renal mass in an.
Structures of antiestrogens and aromatase inhibitors
Wiggers diagram, a correlation of electrical and mechanical events during the cardiac cycle. A phonocardiogram records heart sounds. Source: Cardiovascular.
Negative-feedback control systems
Glucose tolerance testing. A
Survival rates after thyroidectomy for papillary, mixed papillary-follicular, follicular, medullary, and undifferentiated thyroid cancer. Source: Thyroid.
Sectional View of Heart
Dynamic airway compression
(A) Pathway of vitamin D metabolism
Electrical conducting system of the heart
The catecholamines epinephrine (Epi) and norepinephrine (Norepi) are synthesized in chromaffin cells in the adrenal medulla in response to acetylcholine.
Fatty liver. In some cases, the fatty change seen in alcoholics will involve the entire liver (i.e., diffuse fatty liver). Fatty liver can also occur with.
Excitation–Contraction Coupling
The adrenal gland. The adrenal cortex and the adrenal medulla are distinct structures visible in a cross-section of the adrenal gland. The adrenal cortex.
The spinal cord. A. Spinal nerves connect the spinal cord with the periphery. Each spinal nerve has a ventral root containing axons of efferent neurons.
Responses to reduced plasma calcium concentration
The cerebrum. A. Lobes of the cerebral cortex, named according to the skull bones under which they are located. B. Functional classification of regions.
Circulatory changes produced in humans by the slow intravenous infusion of epinephrine and norepinephrine. Source: Chapter 20. The Adrenal Medulla & Adrenal.
Synthesis of calcitriol
Adapted from Aronson L. Twelve tips for teaching reflection at all levels of medical education. Med Teach. 2011;33(3):200–205. Source: EDUCATING FOR PROFESSIONALISM,
Focal nodular hyperplasia
The blood-brain barrier. A
Nutrient or ion regulation of hormone release
The processing of microRNA that is involved in gene regulation by RNA interference. (Reprinted with permission from Brooker RJ: Genetics: Analysis & Principles,
Negative feedback regulation of parathyroid hormone (PTH) release
Vitamin D metabolism and physiologic effects at target organs
Natural history of enteric (typhoid) fever
Semilog graph of the rate of drug elimination in a one-compartment model. Source: One-Compartment Open Model: Intravenous Bolus Administration, Applied.
Papillary renal cell carcinoma
Sciatic nerve stimulation: motor response of the common peroneal or tibial nerves indicate proper localization of the sciatic nerve. Source: Chapter 37.
Negative feedback inhibition of gastric emptying by enterogastrones
Internal hemorrhoids. (Used, with permission, from John Cello, MD.)
Mouth-formed mouth guards. (Left) Without loop strap
The GHRH/GH/IGF-1 system
Fluorescent antibody test
Hierarchy of clinical evidence
A. Use of athletic tape to make an extension block for the wrist. B
Calcium balance. Dietary intake of calcium averages 1 g/d and is a critical determinant of calcium homeostasis. A small fraction is absorbed in the intestinal.
Embryo implantation. The embryo develops for approximately 1 week after fertilization of the egg, forming a blastocyst at the time of implantation. The.
Invasive colonic adenocarcinoma
Effects of PTH and 1,25-dihydroxycholecalciferol on whole body calcium homeostasis. A reduction in plasma calcium stimulates parathyroid hormone secretion.
The straight leg knee immobilizer brace
Myopia (nearsightedness) and hyperopia (farsightedness). A
Supply of practicing physicians in the United States
World Health Organization (WHO) three-step ladder oral analgesic program for managing cancer pain. Source: Chapter 48. Pain Management and Symptom Control,
Adapted with permission from Hiatt WR
Hormones of the adrenal cortex
Adrenal glands. The adrenal glands are composed of a cortex and a medulla, each derived from a different embryologic origin. The cortex is divided into.
[From: Galli : et al: Emergency Orthopedics: The Spine
Negative feedback responses to high effective circulating volume (ECV)
Measurement of static and dynamic compliance during mechanical ventilation. A tidal volume is delivered, causing a peak in airway pressure; dynamic compliance.
Clinical and pathologic effects of hepatocellular failure, which commonly results from conditions associated with acute or chronic necrosis of liver cells.
The Physiology and Pathophysiology of Vitamin D
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Presentation transcript:

Synthesis and activation of vitamin D (cholecalciferol) Synthesis and activation of vitamin D (cholecalciferol). Vitamin D is supplied from the diet and by synthesis from cholesterol-based precursors in the skin. Activation of vitamin D occurs in two stages: 25-hydroxylation in the liver (not regulated) and 1-hydroxylation in the kidney (stimulated by parathyroid hormone and hypophosphatemia). Source: Endocrine Physiology, Medical Physiology: The Big Picture Citation: Kibble JD, Halsey CR. Medical Physiology: The Big Picture; 2015 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/Books/1291/p9780071485678-ch008_f038.png&sec=75577990&BookID=1291&ChapterSecID=75577697&imagename= Accessed: December 28, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.