Nonsteroidal Antiasthma Agents

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Presentation transcript:

Nonsteroidal Antiasthma Agents Chapter 12 RES219 Pharmacology

Three groups Cromolyn-like agents Antileukotrienes Monoclonal antibody

Cromolyn-like agents AKA mast cell stabilizers Prevents rupture of the mast cells Cromolyn Sodium

Antileukotriene Agents Terms: arachidonic acid leukotrienes zileuton (Zyflo) zafirlukast (Accolate) montelukast (Singulair) Blocks production or action of leukotrienes

Monoclonal Antibodies Omalizumab (Xolair) Blocks IgE from binding to the IgE receptor on the surface of mast cell

Antihistamines Histamine stored in tissue mast cell Examples: Claritin Zyrtec Benadryl Allegra

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