Morphine Inhalation by Cancer Patients: A Comparison of Different Nebulization Techniques Using Pharmacokinetic, Spirometric, and Gasometric Parameters  Małgorzata Krajnik, MD, Zygmunt Podolec, MD, Monika Siekierka, MSci, Marzena Sykutera, MSci, Ewa Pufal, MD, Piotr Sobanski, MD, Roman Makarewicz, MD, PhD, Cees Neef, PharmD, PhD, Nieko Punt, MSci, Zbigniew Zylicz, MD, PhD  Journal of Pain and Symptom Management  Volume 38, Issue 5, Pages 747-757 (November 2009) DOI: 10.1016/j.jpainsymman.2009.03.008 Copyright © 2009 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Plasma concentrations of morphine (♦), M3 (▴), and M6 (■) in two patients treated with the BCTS-S method (Patient 1 [a] and Patient 3 [b]) and one patient treated with the BCTS-MC method (Patient 10 [c]). Note in Patients A and B the second peak for the metabolites after about two hours. Journal of Pain and Symptom Management 2009 38, 747-757DOI: (10.1016/j.jpainsymman.2009.03.008) Copyright © 2009 U.S. Cancer Pain Relief Committee Terms and Conditions