Chen Yali;Yin Mengmei;Cao Xuejin;Hu Gang;Xiao Ming;

Slides:

Advertisements

Similar presentations

Ischemia-induced Angiogenesis is Attenuated in Aged Rats

Advertisements

Ischemia-induced Angiogenesis is Attenuated in Aged Rats

Liver cholesterol (mg/g)

Galanin Protects from Caspase-8/12-initiated Neuronal Apoptosis in the Ischemic Mouse Brain via GalR1 Li Yun;Mei Zhu;Liu Shuiqiao;Wang Tong;Li Hui;Li Xiao-Xiao;Han.

LW-AFC Effects on N -glycan Profile in Senescence-Accelerated Mouse Prone 8 Strain, a Mouse Model of Alzheimer#cod#x02019;s Disease Wang Jianhui 1, 2 ;Cheng.

LW-AFC Effects on N -glycan Profile in Senescence-Accelerated Mouse Prone 8 Strain, a Mouse Model of Alzheimer#cod#x02019;s Disease Jianhui Wang 1, 2,

Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids Cai Mengfei 1 ;Zhang Wenting.

Role of Pro-Inflammatory Cytokines and Vitamin D in Probable Alzheimer#cod#x00027;s Disease with Depression Banerjee Anindita 1, 2 ;Kumar Khemka Vineet.

Relationship of Circulating CXCR4 + EPC with Prognosis of Mild Traumatic Brain Injury Patients Yunpeng Lin 1, # ;Lan Lan Luo 2, # ;Jian Sun 1 ;Weiwei.

Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology Lu Jiao 1, 2 ;Duan Xuefeng 1 ;Zhao Wenming 1 ;Wang.

Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer#cod#x02019;s Disease and Related Tauopathies L Castillo-Carranza Diana 1, 2 ;N Nilson.

Plant stanol esters in low-fat yogurt reduces total and low-density lipoprotein cholesterol and low-density lipoprotein oxidation in normocholesterolemic.

Supplemental Figure 1 A B C D E F

CLARITY for High-resolution Imaging and Quantification of Vasculature in the Whole Mouse Brain Zhang Lin-Yuan 1 ;Lin #cod#x0002A;Pan 2 ;Pan Jiaji 3 ;Ma.

Yang Changjun;M. DeMars Kelly;Candelario-Jalil#cod#x0002A; Eduardo;

Diagnostic and Immunosuppressive Potential of Elevated Mir-424 Levels in Circulating Immune Cells of Ischemic Stroke Patients Li Guangwen 1, 2 ;Ma Qingfeng.

Galanin Protects from Caspase-8/12-initiated Neuronal Apoptosis in the Ischemic Mouse Brain via GalR1 Yun Li;Zhu Mei;Shuiqiao Liu;Tong Wang;Hui Li;Xiao-Xiao.

Dopamine Burden Induced the Inactivation of Sonic Hedgehog Signaling to Cognitive Decline in Minimal Hepatic Encephalopathy Ding Saidan 1 ;Yang Jianjing.

Neuroprotective Effect of Caffeic Acid Phenethyl Ester in A Mouse Model of Alzheimer#cod#x00027;s Disease Involves Nrf2/HO-1 Pathway Morroni Fabiana 1.

Mitochondrial Ferritin Protects Hydrogen Peroxide-Induced Neuronal Cell Damage Guofen Gao 1 ;Nan Zhang 1 ;Yue-Qi Wang 1 ;Qiong Wu 1 ;Peng Yu 1 ;Zhen-Hua.

Kidney Blood Press Res 2013;37: DOI: /

Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP Liu Xiangrong 1, 2, 3 ;Wen Shaohong 1, 2,

Role of Pro-Inflammatory Cytokines and Vitamin D in Probable Alzheimer#cod#x00027;s Disease with Depression Anindita Banerjee 1, 2 ;Vineet Kumar Khemka.

Guangxian Zhao 1, # ;Xian W

Therapeutic Potential and Cellular Mechanisms of Panax Notoginseng on Prevention of Aging and Cell Senescence-Associated Diseases Zhao Haiping 1 ;Han Ziping.

Aging Systemic Milieu Impairs Outcome after Ischemic Stroke in Rats

Synergistically Induced Hypothermia and Enhanced Neuroprotection by Pharmacological and Physical Approaches in Stroke Zhang Jun 1 ;Liu Kaiyin 2 ;Elmadhoun.

Evaluation of Hyperbaric Oxygen Treatment in Acute Traumatic Spinal Cord Injury in Rats Using Diffusion Tensor Imaging Sun Wenzhi 1 ;Li Zhuo 2 ;Lu Shibao.

Mitochondrial Ferritin Protects Hydrogen Peroxide-Induced Neuronal Cell Damage Guofen Gao 1 ;Nan Zhang 1 ;Yue-Qi Wang 1 ;Qiong Wu 1 ;Peng Yu 1 ;Zhen-Hua.

Minwen Xu 1 ;Olga Sizova 3 ;Liefeng Wang 2, 3 ;Dong-Ming Su 3 ;

Genistein, the Isoflavone in Soybean, Causes Amyloid Beta Peptide Accumulation in Human Neuroblastoma Cell Line: Implications in Alzheimer#cod#x02019;s.

Novel Modification of Potassium Chloride Induced Cardiac Arrest Model for Aged Mice Liu Huaqin 1, 2 ;Yu Zhui 1, 3 ;Li Ying 1, 4 ;Xu Bin 1, 5 ;Yan Baihui.

Mild Therapeutic Hypothermia Protects the Brain from Ischemia/Reperfusion Injury through Upregulation of iASPP Liu Xiangrong 1, 2, 3 ;Wen Shaohong 1, 2,

Peng Fangyu 1, 2 ;Xie Fang 1 ;Muzik Otto 3, 4 ;

Mash1-dependent Notch Signaling Pathway Regulates GABAergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells Qianfa Long 1,

PARP-1 Inhibition Rescues Short Lifespan in Hyperglycemic C

Temporal Gene Expression Profiles after Focal Cerebral Ischemia in Mice Zhang Chengjie 1, 2, 3 ;Zhu Yanbing 2 ;Wang Song 2, 3 ;Zachory Wei Zheng 1, 2,

Therapeutic Potential and Cellular Mechanisms of Panax Notoginseng on Prevention of Aging and Cell Senescence-Associated Diseases Zhao Haiping 1 ;Han Ziping.

Galanin Protects from Caspase-8/12-initiated Neuronal Apoptosis in the Ischemic Mouse Brain via GalR1 Li Yun;Mei Zhu;Liu Shuiqiao;Wang Tong;Li Hui;Li Xiao-Xiao;Han.

Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids Mengfei Cai 1 ;Wenting.

Deyong Lv 1, 2, 3 ;Jingbo Li 4 ;Hongfu Li 3 ;Yu Fu 5 ;Wei Wang 1, 2 ;

Pkc#cod#x003B4; Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products.

Pkc#cod#x003B4; Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products.

Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids Cai Mengfei 1 ;Zhang Wenting.

Mitochondrial Ferritin Protects Hydrogen Peroxide-Induced Neuronal Cell Damage Guofen Gao 1 ;Nan Zhang 1 ;Yue-Qi Wang 1 ;Qiong Wu 1 ;Peng Yu 1 ;Zhen-Hua.

Mitochondrial Ferritin Protects Hydrogen Peroxide-Induced Neuronal Cell Damage Guofen Gao 1 ;Nan Zhang 1 ;Yue-Qi Wang 1 ;Qiong Wu 1 ;Peng Yu 1 ;Zhen-Hua.

Parity History Determines a Systemic Inflammatory Response to Spread of Ovarian Cancer in Naturally Aged Mice Urzua Ulises 1, 4, 5 ;Chacon Carlos 1 ;Lizama.

Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology Lu Jiao 1, 2 ;Duan Xuefeng 1 ;Zhao Wenming 1 ;Wang.

Pkc#cod#x003B4; Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products.

A B Figure S1. Macroscopic analyses of the ColIITgcog mouse phenotype (female mice) (A) Graph and table of body weights and percentage differences of female.

Rhizoma Coptidis and Berberine as a Natural Drug to Combat Aging and Aging-related Diseases via Anti-oxidation and AMPK Activation Xu Zhifang 1, 2 ;Feng.

Age-Related Gray and White Matter Changes in Normal Adult Brains

Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids Mengfei Cai 1 ;Wenting.

Mash1-dependent Notch Signaling Pathway Regulates GABAergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells Qianfa Long 1,

Mash1-dependent Notch Signaling Pathway Regulates GABAergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells Qianfa Long 1,

Chen Yali;Yin Mengmei;Cao Xuejin;Hu Gang;Xiao Ming;

Chen Yali;Yin Mengmei;Cao Xuejin;Hu Gang;Xiao Ming;

Chen Yali;Yin Mengmei;Cao Xuejin;Hu Gang;Xiao Ming;

© The Author(s) Published by Science and Education Publishing.

Pkc#cod#x003B4; Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products.

Pkc#cod#x003B4; Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products.

Hyperphosphatemia Promotes Senescence of Myoblasts by Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved in Sarcopenia Sosa.

Dopamine Burden Induced the Inactivation of Sonic Hedgehog Signaling to Cognitive Decline in Minimal Hepatic Encephalopathy Saidan Ding 1 ;Jianjing Yang.

LMNA -mutated Rabbits: A Model of Premature Aging Syndrome with Muscular Dystrophy and Dilated Cardiomyopathy Sui Tingting 1 ;Liu Di 1 ;Liu Tingjun 1 ;Deng.

KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update

Dong Feng1 et al. Acta Pharmacol Sin 2015; 36: 1462–1472;

(A) Low-density lipoprotein-cholesterol (LDL-C) values at baseline and after treatment with anagliptin in 20 participants at 12 and 24 weeks. (A) Low-density.

Effects of pterosin A on serum levels of lipid, blood urea nitrogen (BUN), creatinine, aspartate aminotransferase (AST), and alanine aminotransferase (ALT)

Individual lipid measures for high-carbohydrate (n=10) and low-carbohydrate (n=10) ultra-endurance athletes. Individual lipid measures for high-carbohydrate.

Differences in changes in total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides (expressed as mg/dL) between patients with hyperlipidaemia.

Presentation transcript:

Chen Yali;Yin Mengmei;Cao Xuejin;Hu Gang;Xiao Ming; Pro- and Anti-inflammatory Effects of High Cholesterol Diet on Aged Brain Chen Yali;Yin Mengmei;Cao Xuejin;Hu Gang;Xiao Ming; Jiangsu Province Key Laboratory of Neurodegeneration, Nanjing Medical University, Nanjing, China ; Figure 1. Serum cholesterol analysis of young and aged female mice fed a normal or high-cholesterol diet for 8 weeks. A Total cholesterol TC. B High-density lipoprotein cholesterol HDL-C. C Low-density lipoprotein cholesterol LDL-C. Results were expressed as mean #cod#x000B1; SEM. Tests were performed in duplicate on 8 serum samples per group. #cod#x0002A; P #cod#x0003C; 0.05, #cod#x0002A;#cod#x0002A; P #cod#x0003C; 0.01, #cod#x0002A;#cod#x0002A;#cod#x0002A; P #cod#x0003C; 0.001, high cholesterol diet HC mice versus normal control ctrl diet mice; # P #cod#x0003C; 0.05, ## P #cod#x0003C; 0.01, ### P #cod#x0003C; 0.001, aged mice versus young mice. null,null,0(0),null-null. Doi:10.14336/AD.2017.0706