From: Activation of the Alternative Complement Pathway in Vitreous is Controlled by Genetics in Age-Related Macular Degeneration Invest. Ophthalmol. Vis.

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Date of download: 6/3/2016 The Association for Research in Vision and Ophthalmology Copyright © All rights reserved. From: Amyloid-β Deposits Lead.

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From: Activation of the Alternative Complement Pathway in Vitreous is Controlled by Genetics in Age-Related Macular Degeneration Invest. Ophthalmol. Vis. Sci.. 2012;53(10):6628-6637. doi:10.1167/iovs.12-9587 Figure Legend: Immunohistochemical staining for FB on a cross-section through the macula of a 67-year-old female donor with wet AMD diagnosed in the second eye. Red and pink staining reflects FB, brown represents melanin in RPE and choroid. Black arrow points to drusen accumulating between the RPE basement membrane and the BM. Inset shows detail of FB localization in RPE cells, BM, and choroid. Red arrow points to FB staining at the basal side of RPE cells, blue arrow points to FB staining on BM, and white asterisk indicates FB in the lumen of a choroidal vessel. INL, inner nuclear layer; ONL, outer nuclear layer; C, choroid; S, sclera. Scale bar = 100 μm. Date of download: 12/29/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.