Therapeutic Efficacy of Astatine-211–Labeled Trastuzumab on Radioresistant SKOV-3 Tumors in Nude Mice Stig Palm, Ph.D., Tom Bäck, Ingela Claesson, Anna.

Slides:

Advertisements

Similar presentations

Tampon Appearance on Bone Scan Imaging: Case Report Geoffrey M. Currie, MMedRadSc, MAppMngt, MBA, PhD, Matthew Haase, BMedRadSc, Rashid Hashmi, MBBS, MSc,

Advertisements

A Simple Contact Heat Experimental Pain Model for Evaluation of Analgesic Agents in Healthy Volunteers Sunil Kumar Reddy Khambam, MSc, PhD, Madireddy Umamaheshwar.

Other options in the treatment of fecal incontinence Paul A. Lehur, MD, PhD, Emilie Duchalais, MD Seminars in Colon and Rectal Surgery Volume 27, Issue.

Preoperative Evaluations: The Very Last Chance To Identify a Problem With a Pacemaker or Implanted Cardioverter-Defibrillator Marc A. Rozner, PhD, MD Journal.

Professionalism and the work-life balance Thomas S. Huber, MD, PhD Journal of Vascular Surgery Volume 60, Issue 4, Pages (October 2014) DOI:

Image Postprocessing in Digital Radiology—A Primer for Technologists Euclid Seeram, RTR, BSc, MSc, FCAMRT, David Seeram Journal of Medical Imaging and.

A Quantitative Analysis of the Relationship Between Radiation Therapy Use and Travel Time Emma Liu, MM, Pablo Santibáñez, MM, Martin L. Puterman, PhD,

Incidence of Late Rectal and Urinary Toxicities After Three-Dimensional Conformal Radiotherapy and Intensity-Modulated Radiotherapy for Localized Prostate.

Yvan Boutin, PhD, Jacques Hébert, MD

Curative Treatment of Stage I Non-Small-Cell Lung Cancer in Patients With Severe COPD: Stereotactic Radiotherapy Outcomes and Systematic Review David.

Jessica L. Conway, MD, Joseph M

COSMIC: A Regimen of Intensity Modulated Radiation Therapy Plus Dose-Escalated, Raster-Scanned Carbon Ion Boost for Malignant Salivary Gland Tumors: Results.

Correlation of 18F-FDG Avid Volumes on Pre–Radiation Therapy and Post–Radiation Therapy FDG PET Scans in Recurrent Lung Cancer Nadya Shusharina, PhD,

Voice Quality After Treatment of Early Vocal Cord Cancer: A Randomized Trial Comparing Laser Surgery With Radiation Therapy Leena-Maija Aaltonen, MD,

The Case for Prostate Brachytherapy in the Affordable Care Act Era

Toxicity of Gamma Knife Radiosurgery in the Treatment of Intracranial Tumors in Patients With Collagen Vascular Diseases or Multiple Sclerosis Dot Lowell,

Quality of Life and Toxicity From Passively Scattered and Spot-Scanning Proton Beam Therapy for Localized Prostate Cancer Thomas J. Pugh, MD, Mark F.

The Role of Diffusion-Weighted Magnetic Resonance Imaging in the Treatment Response Evaluation of Hepatocellular Carcinoma Patients Treated With Radiation.

Overweight and obesity as risk factors for atrial fibrillation or flutter: The Danish Diet, Cancer, and Health Study Lars Frost, MD, PhD, Lone Juul Hune,

The Use of Hormone Therapy Alone Versus Hormone Therapy and Radiation Therapy for Breast Cancer in Elderly Women: A Population-Based Study Alan M. Nichol,

Cost-Effectiveness Analysis of Stereotactic Body Radiotherapy and Radiofrequency Ablation for Medically Inoperable, Early-Stage Non–Small Cell Lung Cancer

Late Side Effects After Image Guided Intensity Modulated Radiation Therapy Compared to 3D-Conformal Radiation Therapy for Prostate Cancer: Results From.

A technicians' perspective: tips and techniques for using disposable tab electrocardiogram electrodes; an easy to remember method for preventing electrocardiogram.

L-Boronophenylalanine-Mediated Boron Neutron Capture Therapy for Malignant Glioma Progressing After External Beam Radiation Therapy: A Phase I Study

A Dose Escalation and Pharmacodynamic Study of Triapine and Radiation in Patients With Locally Advanced Pancreas Cancer Ludmila Katherine Martin, MD,

18Fluorodeoxyglucose PET Is Prognostic of Progression-Free and Overall Survival in Locally Advanced Pancreas Cancer Treated With Stereotactic Radiotherapy

Dose-Volume Histogram Predictors of Chronic Gastrointestinal Complications After Radical Hysterectomy and Postoperative Concurrent Nedaplatin-Based Chemoradiation.

T. Liu, J. Zhou, S. A. Woodhouse, P. B. Schiff, P. Zhang, K. S

The Pattern of Use of Hypofractionated Radiation Therapy for Early-Stage Breast Cancer in New South Wales, Australia, 2008 to 2012 Geoff P. Delaney,

Lactate-Base 1H Magnetic Spectroscopy Does Not Predict Response and Outcomes in Patients With Stage IV Head and Neck Squamous Cell Carcinoma Q. Le, A.

Higher Biologically Effective Dose of Radiotherapy Is Associated With Improved Outcomes for Locally Advanced Non–Small Cell Lung Carcinoma Treated With.

Individualized Positron Emission Tomography–Based Isotoxic Accelerated Radiation Therapy Is Cost-Effective Compared With Conventional Radiation Therapy:

Close or Positive Margins After Mastectomy for DCIS: Pattern of Relapse and Potential Indications for Radiotherapy Afshin Rashtian, M.D., Shawn Iganej,

Ductal Carcinoma In Situ With Microinvasion: Prognostic Implications, Long-Term Outcomes, and Role of Axillary Evaluation Rahul R. Parikh, M.D., Bruce.

The impact of ipsilateral breast tumor recurrence on cause specific survival in DCIS patients treated with breast conserving therapy or mastectomy C.

Morten Hoyer, Ph. D. , Henrik Roed, D. M. Sc

Jerry D Slater, M. D. , Carl J Rossi, M. D. , Les T Yonemoto, M. D

Five-Year Biochemical Results, Toxicity, and Patient-Reported Quality of Life After Delivery of Dose-Escalated Image Guided Proton Therapy for Prostate.

A New Model for Imaging and Radiation Therapy Quality Assurance in the National Clinical Trials Network of the National Cancer Institute Thomas J. FitzGerald,

Obituary and Tribute to John “Jack” Francis Fowler, PhD, DSc ( )

Continuing Risk of Ipsilateral Breast Relapse After Breast-Conserving Therapy at Long- Term Follow-up Bas Kreike, M.D., Augustinus A.M. Hart, M.Sc., Tony.

Frederiek M. Lever, MD, Irene M. Lips, MD, PhD, Sjoerd P. M

Timing of Radiation Therapy and Chemotherapy After Breast-Conserving Surgery for Node-Positive Breast Cancer: Long-Term Results From International Breast.

Dose–Volume Relationships Associated With Temporal Lobe Radiation Necrosis After Skull Base Proton Beam Therapy Mark W. McDonald, MD, Okechukwu R. Linton,

Lifetime Increased Cancer Risk in Mice Following Exposure to Clinical Proton Beam– Generated Neutrons Leo E. Gerweck, PhD, Peigen Huang, MD, Hsiao-Ming.

Higher-Than-Conventional Radiation Doses in Localized Prostate Cancer Treatment: A Meta-analysis of Randomized, Controlled Trials Gustavo Arruda Viani,

MR-OPERA: A Multicenter/Multivendor Validation of Magnetic Resonance Imaging–Only Prostate Treatment Planning Using Synthetic Computed Tomography Images

Salvage Stereotactic Body Radiotherapy (SBRT) Following In-Field Failure of Initial SBRT for Spinal Metastases Isabelle Thibault, MD, Mikki Campbell,

Adjuvant Therapy in High-Risk Stage III Cutaneous Melanoma

International Journal of Radiation Oncology • Biology • Physics

Vaginal Motion and Bladder and Rectal Volumes During Pelvic Intensity-Modulated Radiation Therapy After Hysterectomy Anuja Jhingran, M.D., Mohammad Salehpour,

Active Breathing Control in Combination With Ultrasound Imaging: A Feasibility Study of Image Guidance in Stereotactic Body Radiation Therapy of Liver.

Administered activity and metastatic cure probability during radioimmunotherapy of ovarian cancer in nude mice with 211At-MX35 F(ab′)2 Jörgen Elgqvist,

Gregory S. Weingart, MD, Jestin N. Carlson, MD, Clifton W

Conducting a Research Interview

High-Dose-Rate Brachytherapy Boost for Prostate Cancer: Comparison of Two Different Fractionation Schemes Tania Kaprealian, M.D., Vivian Weinberg, Ph.D.,

Overweight and obesity as risk factors for atrial fibrillation or flutter: The Danish Diet, Cancer, and Health Study Lars Frost, MD, PhD, Lone Juul Hune,

Volume 168, Issue 4, (October 2002)

Overview of Current Learning Theories for Medical Educators

Trend in Mortality after Stroke with Atrial Fibrillation

The effect of regionalization on outcome in pulmonary lobectomy: A Canadian national study Christian J. Finley, MD, MPH, Anna Bendzsak, MD, George Tomlinson,

Wilberto Nieves-Neira, J. Julie Kim, Daniela Matei

Anna Danielsson, RPT, Med fac lic, Carin Willén, RPT, PhD, Katharina S

The lord of the rings Antonio Miceli, MD, PhD

Confessions of a journal junkie

Study Designs in Patient-Oriented Research

Treatment of Colorectal Cancer

Should Nurse Practitioners Who Are Covered by Large Group Malpractice Plans Also Maintain Their Own Malpractice Coverage? Donald Gardenier The Journal.

Supportive care for patients with renal disease: Time for action

Benjamin Chaigne, MD, Hervé Watier, MD, PhD

Presentation transcript:

Therapeutic Efficacy of Astatine-211–Labeled Trastuzumab on Radioresistant SKOV-3 Tumors in Nude Mice Stig Palm, Ph.D., Tom Bäck, Ingela Claesson, Anna Danielsson, Ph.D., Jörgen Elgqvist, Ph.D., Sofia Frost, M.Sc., Ragnar Hultborn, M.D., Ph.D., Holger Jensen, Ph.D., Sture Lindegren, Ph.D., Lars Jacobsson, Ph.D. International Journal of Radiation Oncology • Biology • Physics Volume 69, Issue 2, Pages 572-579 (October 2007) DOI: 10.1016/j.ijrobp.2007.06.023 Copyright © 2007 Elsevier Inc. Terms and Conditions

Fig. 1 Percentage of injected activity per gram (%IA/g) for intraperitoneally injected astatine-211 (211At)-trastuzumab (∼400 kBq on ∼5 μg monoclonal antibody [mAb]) in organs at 1.3, 3.5, 9, and 19 h (n = 5 for each time point) after injection. Values corrected for radioactive decay and presented as the mean ± standard error of mean (standard error of mean is one standard deviation of mean). ∗Activity concentration in thyroid determined from throat specimens (see “Methods and Materials” section). International Journal of Radiation Oncology • Biology • Physics 2007 69, 572-579DOI: (10.1016/j.ijrobp.2007.06.023) Copyright © 2007 Elsevier Inc. Terms and Conditions