Ultrasonography of the Colon in Pediatric Ulcerative Colitis: A Prospective, Blind, Comparative Study with Colonoscopy Fortunata Civitelli, MD, Giovanni.

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Presentation transcript:

Ultrasonography of the Colon in Pediatric Ulcerative Colitis: A Prospective, Blind, Comparative Study with Colonoscopy Fortunata Civitelli, MD, Giovanni Di Nardo, MD, PhD, Salvatore Oliva, MD, Federica Nuti, MD, PhD, Federica Ferrari, MD, Anna Dilillo, MD, Franca Viola, MD, Nadia Pallotta, MD, Salvatore Cucchiara, MD, PhD, Marina Aloi, MD, PhD The Journal of Pediatrics Volume 165, Issue 1, Pages 78-84.e2 (July 2014) DOI: 10.1016/j.jpeds.2014.02.055 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 2 Concordance between US and endoscopy for location of disease. The Journal of Pediatrics 2014 165, 78-84.e2DOI: (10.1016/j.jpeds.2014.02.055) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 3 Dot plot of BWT and endoscopic disease severity in all bowel segments examined (n = 150). The mean value of BWT was significantly different between normal segments and moderately and severely inflamed segments whereas there was no statistically significant difference between normal and mildly inflamed segments nor between segments with moderate and severe disease at endoscopy. The Journal of Pediatrics 2014 165, 78-84.e2DOI: (10.1016/j.jpeds.2014.02.055) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 5 Concordance between US and endoscopy for disease activity. The Journal of Pediatrics 2014 165, 78-84.e2DOI: (10.1016/j.jpeds.2014.02.055) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Flow chart illustrating the number of recruited subjects (n = 60) and the number of eligible patients (n = 50) who underwent a complete diagnostic work-up and were finally included in the study. The Journal of Pediatrics 2014 165, 78-84.e2DOI: (10.1016/j.jpeds.2014.02.055) Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 4 US and endoscopic appearance of the A, left and B, transverse colon in a patient with active disease. A, Longitudinal and transverse scan of the descending colon. Thickened BW with presence of color signals and loss of haustra coli. The BW stratification is preserved. B, Transversal US scan of the transverse colon showing thickened BW, increased vascularity, and loss of the normal stratification. Note the presence of enlarged mesenteric lymph nodes (arrow). The Journal of Pediatrics 2014 165, 78-84.e2DOI: (10.1016/j.jpeds.2014.02.055) Copyright © 2014 Elsevier Inc. Terms and Conditions