Effects of various flow types on maternal hemodynamics during fetal bypass: Is there nitric oxide release during pulsatile perfusion? Catherine Vedrinne,

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Presentation transcript:

Effects of various flow types on maternal hemodynamics during fetal bypass: Is there nitric oxide release during pulsatile perfusion? Catherine Vedrinne, MDa, François Tronc, MDb, Stéphane Martinot, MVDc, Jacques Robin, MDb, Claude Garhibd, Jean Ninet, MDb, Jean Jacques Lehot, MDa, Michel Franck, MVDc, Gérard Champsaur, MDb The Journal of Thoracic and Cardiovascular Surgery Volume 116, Issue 3, Pages 432-439 (September 1998) DOI: 10.1016/S0022-5223(98)70009-1 Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 1 Experimental protocol. Administration of ACH to fetuses after 40 min of bypass (T8) and to ewes after the end of fetuses bypass (T11). ↓N-NA injection in the PBF group after 30 minutes of bypass. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 432-439DOI: (10.1016/S0022-5223(98)70009-1) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 2 Maternal CO (L · min), evolution, and between groups comparison: T0, induction, T3 before bypass; T4 = 10 min; T6 = 30 min; T8 = 40 min; T11 = 60 min of bypass. ●PF versus SF group, P < .05. ★★PBF group versus SF group, P < .05. ● PF versus PBF group, P < .05. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 432-439DOI: (10.1016/S0022-5223(98)70009-1) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 3 Maternal systemic vascular resistances (IU), evolution, and between groups comparison: T0, induction, T3 before bypass; T4 = 10 min; T6 = 30 min; T8 = 40 min; T11= 60 min of bypass. ★PF versus SF group, P < .05. ★★PBF group versus SF group, P < .05. ● PF versus PBF group, P < .05. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 432-439DOI: (10.1016/S0022-5223(98)70009-1) Copyright © 1998 Mosby, Inc. Terms and Conditions