876 fetal cord blood DNA samples

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876 fetal cord blood DNA samples Supplemental Figure 1. 876 fetal cord blood DNA samples available for genome-wide methylation analysis using Infinium Human Methylation 450 BeadChip 3 samples excluded: missing chronological gestational age data and an outlier with epigenetic gestational age >5 standard deviations 817 fetal cord blood DNA samples valid information on genome-wide methylation and genotype data 814 fetal cord blood DNA samples with child epigenetic gestational age 825 fetal cord blood DNA samples passed quality control procedures and had full information on genome-wide methylation 8 samples excluded: call rate below 98%, IBD estimate > 0.125 and could not be resolved and discrepancies between phenotypic and genotypic sex in genome-wide genotype data 42 samples excluded: duplicates, outliers in the median intensities, cross-hybridizing probes or probes containing SNPs and CpGs with a detection P-value > 0.01 in at least 50% of the samples, due to location on chromosome X or Y, or sex discrepancies 834 fetal cord blood DNA samples full information on genome-wide methylation and DNAm gestational age was calculated 9 samples excluded: maternal blood contamination