A New Locus for Autosomal Recessive Hereditary Spastic Paraplegia Maps to Chromosome 16q24.3 Giuseppe De Michele, Maurizio De Fusco, Francesca Cavalcanti,

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A New Locus for Autosomal Recessive Hereditary Spastic Paraplegia Maps to Chromosome 16q24.3 Giuseppe De Michele, Maurizio De Fusco, Francesca Cavalcanti, Alessandro Filla, Roberto Marconi, Giampiero Volpe, Antonella Monticelli, Andrea Ballabio, Giorgio Casari, Sergio Cocozza The American Journal of Human Genetics Volume 63, Issue 1, Pages 135-139 (July 1998) DOI: 10.1086/301930 Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 1 Pedigree of the AR-HSP family and haplotype analysis of markers (listed from top to bottom) D16S511, D16S3037, D16S520, D16S3048, D16S413, D16S3023, and D16S303. The American Journal of Human Genetics 1998 63, 135-139DOI: (10.1086/301930) Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 2 Multipoint LOD score analysis of the distal 16q region. Distances are in centimorgansHald from D16S511, which was taken arbitrarily as 0. The American Journal of Human Genetics 1998 63, 135-139DOI: (10.1086/301930) Copyright © 1998 The American Society of Human Genetics Terms and Conditions