Acute lymphoid leukemia (ALL) Acute lymphoid leukemia (ALL). The four white blood cells (lymphoblasts) in the photomicrograph have a high nuclear to cytoplasmic ratio, and the chromatin in the nuclei is finely dispersed and homogenous in appearance. These changes are consistent with an acute leukemia of lymphocytic origin. Wright-Giemsa, 1000×. Source: Chapter 12. Hematopathology, Pathology: The Big Picture Citation: Kemp WL, Burns DK, Brown TG. Pathology: The Big Picture; 2008 Available at: https://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/Books/kemp1/kemp1_c012f010.png&sec=41570551&BookID=499&ChapterSecID=41568295&imagename= Accessed: December 31, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved