Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control Kelly Wong-McGrath, MS,

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Presentation transcript:

Internet-Based Monitoring in the Severe Asthma Research Program Identifies a Subgroup of Patients With Labile Asthma Control Kelly Wong-McGrath, MS, Loren C. Denlinger, MD, PhD, Eugene R. Bleecker, MD, Mario Castro, MD, Ben Gaston, MD, Elliot Israel, MD, Nizar N. Jarjour, MD, David T. Mauger, PhD, Stephen Peters, MD, PhD, Brenda R. Phillips, MS, Sally E. Wenzel, MD, John V. Fahy, MD, Michael C. Peters, MD CHEST DOI: 10.1016/j.chest.2017.10.017 Copyright © 2017 Terms and Conditions

Figure 1 Survey adherence among patients who participated in the Internet-based Monitoring Systems (IBS+) survey. A, The percentage of completed surveys (x-axis) among the 259 IBS+ participants. Few subjects completed < 20% of the available surveys, and the majority of subjects completed > 40% of the available surveys. B, Following completion of the first survey, the percentage of participants who completed surveys remained stable over the course of the following year. CHEST DOI: (10.1016/j.chest.2017.10.017) Copyright © 2017 Terms and Conditions

Figure 2 Examples of participants with high ACT variability. A, Participant who had many months of good control with episodic drops in control. B, Participant who fluctuated dramatically across months. C, Participant with high variability but no periods of good control. ACT = Asthma Control Test. CHEST DOI: (10.1016/j.chest.2017.10.017) Copyright © 2017 Terms and Conditions

Figure 3 Cumulative incidence of asthma exacerbations at 6-month and 12-month follow-up stratified by Asthma Control Test (ACT) variability tertiles. Subjects with high ACT variability (tertile 3) experienced a higher incidence of severe and nonsevere asthma exacerbations at the 12-month follow up. A, Cumulative incidence of all asthma exacerbations, as defined by any of the following: (1) unscheduled visit to a physician's office, (2) oral corticosteroid burst, (3) ED visit, or (4) hospital admission. B, Cumulative incidence of severe asthma exacerbations, limited to one of the following: (1) ED visit or (2) hospital admission. CHEST DOI: (10.1016/j.chest.2017.10.017) Copyright © 2017 Terms and Conditions