Stefania Bellone, PhD, Hemendrah R. Shah, MD, Jesse K

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Presentation transcript:

Recurrent endometrial carcinoma regression with the use of the aromatase inhibitor anastrozole Stefania Bellone, PhD, Hemendrah R. Shah, MD, Jesse K. McKenney, MD, Pamela J.B. Stone, MD, Alessandro D. Santin, MD American Journal of Obstetrics & Gynecology Volume 199, Issue 3, Pages e7-e10 (September 2008) DOI: 10.1016/j.ajog.2008.04.012 Copyright © 2008 Mosby, Inc. Terms and Conditions

FIGURE 1 CT scans of recurrent endometrioid adenocarcinoma before the beginning of anastrozole therapy Representative chest (left) and pelvis (right) CT scans before the beginning of anastrozole therapy (upper panel: lung nodule = 1.5 × 1.8 cm; pelvic mass = 4 × 5 cm), after 6 courses of chemotherapy (middle panel: lung nodule = complete response; pelvic mass = 2.4 × 1.8 cm), and after 9 months from the beginning of Arimidex therapy (lower panel: lung nodule = complete response; pelvic mass = 2.0 × 1.4 cm). The arrows indicate metastatic/recurrent target lesions in the lung and pelvis that show regression to therapy. Bellone. Recurrent endometrial carcinoma. Am J Obstet Gynecol 2008. American Journal of Obstetrics & Gynecology 2008 199, e7-e10DOI: (10.1016/j.ajog.2008.04.012) Copyright © 2008 Mosby, Inc. Terms and Conditions

FIGURE 2 Immunohistochemistry staining of recurrent endometrioid adenocarcinoma Hematoxylin-eosin stain of endometrioid adenocarcinoma that was recurrent in the lung (upper panel: original magnification, ×400) with positive ER immunostains (lower panel: original magnification, ×400). Bellone. Recurrent endometrial carcinoma. Am J Obstet Gynecol 2008. American Journal of Obstetrics & Gynecology 2008 199, e7-e10DOI: (10.1016/j.ajog.2008.04.012) Copyright © 2008 Mosby, Inc. Terms and Conditions