Tachycardia-induced cardiomyopathy in the ovine heart: Mitral annular dynamic three- dimensional geometry Tomasz A. Timek, MDa, Paul Dagum, MD, PhDa,

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Presentation transcript:

Tachycardia-induced cardiomyopathy in the ovine heart: Mitral annular dynamic three- dimensional geometry Tomasz A. Timek, MDa, Paul Dagum, MD, PhDa, David T. Lai, FRACSa, David Liang, MD, PhDb, George T. Daughters, MSa,c, Frederick Tibayan, MDa, Neil B. Ingels, PhDa,c, D.Craig Miller, MDa The Journal of Thoracic and Cardiovascular Surgery Volume 125, Issue 2, Pages 315-324 (February 2003) DOI: 10.1067/mtc.2003.80 Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions

Fig. 1 Schematic representation of the mitral annular marker array used in the study. Markers 2 and 4 correspond to the right and left fibrous trigones, respectively. ACOM, Anterior commissure; PCOM, posterior commissure; AML, anterior mitral leaflet; PML, posterior mitral leaflet. The Journal of Thoracic and Cardiovascular Surgery 2003 125, 315-324DOI: (10.1067/mtc.2003.80) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions

Fig. 2 Mitral annular (MA) total perimeter, muscular perimeter, fibrous perimeter (left), mitral annular area, annular S-L diameter, and annular C-C diameter (right) at baseline (filled squares) and after TIC (open squares). A 650-ms time window centered at ED (t = 0) is illustrated for all variables. Error bars indicate 1 SEM. The Journal of Thoracic and Cardiovascular Surgery 2003 125, 315-324DOI: (10.1067/mtc.2003.80) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions

Fig. 3 Mitral annular area at baseline (squares) and with TIC (triangles) before (filled symbols) and after (open symbols) dobutamine (DB) infusion. A 650-ms time window centered at ED (t = 0) is shown for all variables. The Journal of Thoracic and Cardiovascular Surgery 2003 125, 315-324DOI: (10.1067/mtc.2003.80) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions

Fig. 4 Left, Three-dimensional reconstruction of the mitral annulus at ED (top) and ES (bottom) at baseline (filled squares) and after TIC (open circles). Right, Rotated view of each reconstruction as viewed from the lateral-septal annulus to illustrate the saddle shape of the annulus. #3, Saddle horn marker; ACOM, anterior commissure; PCOM, posterior commissure. The Journal of Thoracic and Cardiovascular Surgery 2003 125, 315-324DOI: (10.1067/mtc.2003.80) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions

Fig. 5 End-diastolic distance of each annular marker from the least-squares plane fitted to all annular markers before (filled squares) and after (open squares) development of TIC. Marker numbers, as shown in Figure 1. Error bars indicate 1 SEM. *P <.05 and **P <.01 by means of t test for paired comparisons. The Journal of Thoracic and Cardiovascular Surgery 2003 125, 315-324DOI: (10.1067/mtc.2003.80) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions

Fig. 6 Septal annulus flexion expressed as the distance of the saddle horn marker to the least-squares plane of the lateral annulus before (filled squares) and after (open squares) TIC. A 650-ms time window centered at ED (dashed line) is shown. Error bars indicate 1 SEM. The Journal of Thoracic and Cardiovascular Surgery 2003 125, 315-324DOI: (10.1067/mtc.2003.80) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions