C. The arcuate neurons shown in part B project to multiple regions of the hypothalamus. The paraventricular nucleus (PVN) is a convergence zone for many signals involved in energy (and fluid) balance. Neurons in this nucleus synthesize several peptides that decrease food intake, including corticotropin-releasing hormone (CRH), thyrotropin-releasing hormone (TRH), and oxytocin (OXY). The perifornical area (PFA) and lateral hypothalamic area (LHA) contain neurons that synthesize orexins and melanin concentrating hormone (MCH), peptides that stimulate food intake. (Adapted, with permission, from Schwartz et al. 2000.) Source: Homeostasis, Motivation, and Addictive States, Principles of Neural Science, Fifth Editon Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available at: https://neurology.mhmedical.com/DownloadImage.aspx?image=/data/books/1049/kan_ch49_f003.png&sec=59145569&BookID=1049&ChapterSecID=59138681&imagename= Accessed: January 02, 2018 Copyright © 2018 McGraw-Hill Education. All rights reserved