From: Experimental Glaucoma and Optic Nerve Transection Induce Simultaneous Upregulation of Proapoptotic and Prosurvival Genes Invest. Ophthalmol. Vis. Sci.. 2006;47(6):2491-2497. doi:10.1167/iovs.05-0996 Figure Legend: Quantitative real-time PCR analysis of Gadd45a, IAP-1, Ei24, and Cdk2 gene expression in experimental glaucoma. The proapoptotic gene Gadd45a and the presurvival gene IAP-1 were significantly upregulated 1 month after the induction of elevated IOP. At 2 months, however, only Gadd45a was still upregulated. *P < 0.05; **P < 0.01. C, control naïve animals (n = 4). Date of download: 1/2/2018 The Association for Research in Vision and Ophthalmology Copyright © 2018. All rights reserved.