TERT gene amplification is associated with poor outcome in acral lentiginous melanoma  Alba Diaz, MD, Joan Anton Puig-Butillé, PhD, Concha Muñoz, Dolors.

Slides:



Advertisements
Similar presentations
Surgical margins for melanoma in situ
Advertisements

Optimal time to provide skin cancer and photoprotection education to pediatric solid organ transplant recipients  Lily Chen, BA, Feng Gao, MD, PhD, MPH,
Lauren Kwa, BA, Jonathan I. Silverberg, MD, PhD, MPH 
A girl with a solitary red bulla
Yul W. Yang, MD, PhD, David J. DiCaudo, MD 
Psoriasis: Latitude does make a difference
Sweet's panniculitis associated with metastatic breast cancer
TERT and AURKA Gene Copy Number Gains Enhance the Detection of Acral Lentiginous Melanomas by Fluorescence in Situ Hybridization  Alba Diaz, Joan Anton.
Baldness reversed by chemotherapy
Paclitaxel for progressive basal cell carcinoma
Megan Wood, MD, Tom Raisanen, MD, Ingrid Polcari, MD 
Squamous cell carcinoma over tattoos
Expression of PD-L1 in mastocytosis
Array of cutaneous adverse effects associated with sorafenib
Hypertrichosis around a leg ulcer being treated with prostaglandin E1 ointment  Tetsuya Honda, MD, PhD, Satoshi Koreeda, MD, PhD, Yoshiki Miyachi, MD,
Jacqueline J. Russo, MD, Keira L. Barr, MD, Larissa Z
Elana Putterman, BS, Leslie Castelo-Soccio, MD, PhD 
Sarah Sung, MD, Alexa B. Kimball, MD, MPH 
Surveillance and assessment of occupational dermatitis using Rhode Island workers' compensation data 1998 to 2002  Irwin B. Horwitz, PhD, Brian P. McCall,
Pediatric teledermatology: Observations based on 429 consults
JAK inhibitors in dermatology: The promise of a new drug class
Whole-exome sequencing reveals differences between nail apparatus melanoma and acral melanoma  Minho Lee, PhD, Jonghwan Yoon, BS, Yeun-Jun Chung, MD,
Dermoscopy for diagnosis of pediculosis capitis
A definitive case of metastatic folliculotropic melanoma
Effect of appearance-based education compared with health-based education on sunscreen use and knowledge: A randomized controlled trial  William Tuong,
Pharmacy costs of specialty medications for plaque psoriasis in the United States  Eric J. Yang, BS, Kristen M. Beck, MD, Sahil Sekhon, MD, Tina Bhutani,
Smoking and risk of psoriasis: A nationwide cohort study
Pilot study of a skin cancer education curriculum for medical students
Applying for dermatology residency is difficult and expensive
Kishore L. Jayakumar, BS, Sara S. Samimi, MD 
Treatment of toxic epidermal necrolysis in North America
Lack of TERT promoter mutations in melanomas with extensive regression
Chauncey C. Caldwell, MD, Sami K. Saikaly, MD, Robert P
Alopecia areata Journal of the American Academy of Dermatology
Google search trends for tanning salons: Temporal patterns indicate peak interest in mid spring  Derek D. Reed, PhD, BCBA-D  Journal of the American Academy.
“Strawberry gums” in sarcoidosis
A survey-based study on nail examinations at an American Academy of Dermatology free skin cancer screening  Dayoung Ko, BS, Shari R. Lipner, MD, PhD 
SALT II: A new take on the Severity of Alopecia Tool (SALT) for determining percentage scalp hair loss  Elise A. Olsen, MD, Douglas Canfield, BS  Journal.
Fever, eosinophilia, and a rash
Repigmentation of hair associated with melanoma in situ of scalp
Infectious rash after riding elephants
Cutaneous involvement in multiple myeloma mimicking acral-lentiginous melanoma  Antonio Martorell, MD, Fernando Millan-Parrilla, MD, Enrique Gimeno-Carpio,
Minichromosome maintenance protein expression in benign nevi, dysplastic nevi, melanoma, and cutaneous melanoma metastases  Alan S. Boyd, MD, Bashar Shakhtour,
Lip edema Journal of the American Academy of Dermatology
Isotretinoin for high-grade or refractory epidermal growth factor receptor inhibitor-related acneiform papulopustular eruptions  Herbert C. Chiang, MD,
Pooja H. Rambhia, BA, Ivan J. Stojanov, DMD, Joshua Arbesman, MD 
Appearance of lentigines in psoriasis patients treated with apremilast
Medicaid acceptance among pediatric dermatologists
Oral allergy syndrome and contact urticaria to apples
Recent dermatology visit is associated with thinner Breslow depth nodular melanomas  Erin X. Wei, MD, Lucy Chen, MD, Fangchao Ma, PhD, Jonette Keri, MD,
Christopher T. Cassetty, MD, Andrew F. Alexis, MD, MPH, Jerome L
Modification of the nail psoriasis severity index
Tofacitinib therapy for children with severe alopecia areata
Gordon W. Jung, MD, Patricia T. Ting, MSc, MD, Thomas G
Digital photography in the diagnosis of scabies
Penile condylomata? Traumatic neuromas!
A new oral anticoagulant in the setting of dermatologic surgery
A simple algorithm for evaluating dermatologic disease in critically ill patients: A study based on retrospective review of medical intensive care unit.
Eyebrow transplantation: Alternative body sites as a donor source
Gaps in pain management in dermatology: A needs assessment from Canada
A grayscale photograph with high dynamic range taken under a Wood's lamp for better recognition of vitiligo lesions  Jung Min Bae, MD, PhD, Tae Young.
Deficiency of sun protection advertising exists in consumer magazines across demographic groups and varies by target demographic  Lauren E. Wiznia, MD,
Numerous hyperpigmented macules of the oral mucosa
Brittany G. Craiglow, MD, Brett A. King, MD, PhD 
Randomized study of topical tacrolimus ointment as possible treatment for resistant idiopathic pruritus ani  Erwin Suys, MD  Journal of the American Academy.
“Boot foot” with pseudomonas colonization
Whitish elbow nodules in a healthy 11-year-old girl
Reporting of harm and safety results in randomized controlled trials published in 5 dermatology journals  Cynthia Haddad, PharmD, MSc, Odette Berline.
Anastasia O. Kurta, DO, Daisy Dai, PhD, Eric S
Stuart M. Goldsmith, MD, Armand B. Cognetta, MD 
Presentation transcript:

TERT gene amplification is associated with poor outcome in acral lentiginous melanoma  Alba Diaz, MD, Joan Anton Puig-Butillé, PhD, Concha Muñoz, Dolors Costa, PhD, Anna Díez, MSc, Adriana Garcia-Herrera, MD, PhD, Cristina Carrera, MD, PhD, Celia Badenas, PhD, Francesc Solé, PhD, Josep Malvehy, MD, PhD, Susana Puig, MD, PhD, Llucia Alos, MD, PhD  Journal of the American Academy of Dermatology  Volume 71, Issue 4, Pages 839-841 (October 2014) DOI: 10.1016/j.jaad.2014.05.035 Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 FISH picture of an acral lentiginous melanoma harboring TERT amplification. It shows a higher number of TERT copies (green signals) when compared to the control gene MCTP1 (red signals) (Original magnification: ×1000.) Journal of the American Academy of Dermatology 2014 71, 839-841DOI: (10.1016/j.jaad.2014.05.035) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions