Negative feedback responses to high effective circulating volume (ECV) Negative feedback responses to high effective circulating volume (ECV). ANP, atrial natriuretic peptide. Source: Renal Physiology and Acid-Base Balance, Medical Physiology: The Big Picture Citation: Kibble JD, Halsey CR. Medical Physiology: The Big Picture; 2015 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/1291/p9780071485678-ch006_f030.png&sec=75577224&BookID=1291&ChapterSecID=75577039&imagename= Accessed: January 02, 2018 Copyright © 2018 McGraw-Hill Education. All rights reserved