Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M

Slides:

Advertisements

Similar presentations

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

Advertisements

Reducing relative humidity to control the house dust mite Dermatophagoides farinae Larry G. Arlian, PhD, Jacqueline S. Neal, BS, DiAnn L. Vyszenski-Moher,

House dust mite avoidance measures improve peak flow and symptoms in patients with allergy but without asthma: A possible delay in the manifestation of.

Treating acute rhinosinusitis: Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo Eli O. Meltzer, MD, Claus Bachert,

The effects of upper respiratory infection on T-cell proliferation and steroid sensitivity of asthmatics Elcio O. Vianna, MD, PhD, Jay Westcott, PhD,

The editors’ choice Journal of Allergy and Clinical Immunology

Comparative efficacy and anti-inflammatory profile of once-daily therapy with leukotriene antagonist or low-dose inhaled corticosteroid in patients with.

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD

Fluticasone furoate nasal spray: A single treatment option for the symptoms of seasonal allergic rhinitis Harold B. Kaiser, MD, Robert M. Naclerio, MD,

Rosa Codina, PhD, Richard F. Lockey, MD

Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis Paul H. Ratner,

Is 9 more than 2 also in allergic airway inflammation?

Practice Notes from the AAAI

Badrul A. Chowdhury, MD, PhD

Hydroxychloroquine improves airflow and lowers circulating IgE levels in subjects with moderate symptomatic asthma B.Lauren Charous, MD, Elkan F. Halpern,

Mark T. S. Chan, MDa, Donald Y. M. Leung, MD, PhDb, Stanley J

The Editors’ Choice Journal of Allergy and Clinical Immunology

Elephantiasis nostras: A case report

The impact of allergic rhinitis on bronchial asthma

Nonadherence to Asthma Treatment: Getting Unstuck

Side effects of inhaled corticosteroids

Michael Mellon, MD Journal of Allergy and Clinical Immunology

Practice Notes from the AAAAI

Paul M. O’Byrne, MB, FRCPI, FRCP(C)a, Soren Pedersen, MD, PhDb

A methodological assessment of diurnal variability of peak flow as a basis for comparing different inhaled steroid formulations John H. Toogood, MD,

A review of the current guidelines for allergic rhinitis and asthma

Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation Leif Bjermer, MD Journal of Allergy.

Early decreases in blood eosinophil levels with reslizumab

Physician-targeted program on inhaled therapy for childhood asthma

News & Notes Journal of Allergy and Clinical Immunology

Circadian variation of sputum inflammatory cells in mild asthma

Direct exposure of carpets to sunlight can kill all mites

Inflammatory cells, cytokine and chemokine expression in asthma immunocytochemistry and in situ hybridization Qutayba Hamid, MD, PhD, Editor Journal.

Salmeterol and fluticasone propionate combined in a new powder inhalation device for the treatment of asthma: A randomized, double-blind, placebo-controlled.

The editors' choice Journal of Allergy and Clinical Immunology

Claus Bachert, MD, PhD, Cezmi A. Akdis, MD

Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma William.

Patterns of pollen cross-allergenicity

Exercise-induced bronchoconstriction in children: Montelukast attenuates the immediate-phase and late-phase responses Raul E. Melo, MD, Dirceu Solé,

Clinical need for a nebulized corticosteroid

Treating acute rhinosinusitis: Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo Eli O. Meltzer, MD, Claus Bachert,

Autophagy: Nobel Prize 2016 and allergy and asthma research

A comparison of multiple doses of fluticasone propionate and beclomethasone dipropionate in subjects with persistent asthma Gordon D. Raphael, MDa, Robert.

News & Notes Journal of Allergy and Clinical Immunology

Low-dose inhaled fluticasone propionate versus oral zafirlukast in the treatment of persistent asthma Eugene R. Bleecker, MDa, Michael J. Welch, MDb,

Observations on emerging patterns of asthma in our society

Emma Broadfield, MRCP, Tricia M

News Beyond Our Pages Journal of Allergy and Clinical Immunology

Stanley J. Szefler, MD, Richard J

Preparing patients and health professionals for the transition to chlorofluorocarbon-free inhalers: The British perspective Helen Donohoe, MSc (Econ)

Practice Notes from the AAAI

Leukotriene receptor antagonists in asthma therapy

Washing the dog reduces dog allergen levels, but the dog needs to be washed twice a week Tessa Hodson, BSc, Adnan Custovic, MD, Angela Simpson, MD, Martin.

Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane- beclomethasone extrafine inhalation aerosol), in asthma Jennifer.

The Editors' Choice Journal of Allergy and Clinical Immunology

Further studies on the chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy Diane J. Pincus, MD, Teresa R. Humeston,

Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M

Effect of continuing or finishing high-level sports on airway inflammation, bronchial hyperresponsiveness, and asthma: A 5-year prospective follow-up.

Footnotes1 Journal of Allergy and Clinical Immunology

National trends in asthma visits and asthma pharmacotherapy,

Macrolide antibiotics and asthma treatment

Larry C. Borish, MDa, Harold S

Exhaled carbon monoxide levels after a course of oral prednisone in children with asthma exacerbation Stefania Zanconato, MD, PhD, Massimo Scollo, MD,

Budesonide Inhalation Suspension Versus Montelukast in Children Aged 2 to 4 Years with Mild Persistent Asthma Stanley J. Szefler, MD, Lars-Goran Carlsson,

The preventive effect and duration of action of two doses of inhaled furosemide on exercise-induced asthma in children Elio Novembre, MD, Gianfranco.

Asthma symptoms and airway hyperresponsiveness are lower during treatment with nedocromil sodium than during treatment with regular inhaled albuterol

News & Notes Journal of Allergy and Clinical Immunology

Advances in pediatric asthma in 2007

Safety and efficacy of repeated monthly carboplatin desensitization

Natural history of cow’s milk allergy

Presentation transcript:

Chronotherapy of asthma with inhaled steroids: The effect of dosage timing on drug efficacy Diane J. Pincus, MD, Stanley J. Szefler, MD, Lynn M. Ackerson, PhD, Richard J. Martin, MD Journal of Allergy and Clinical Immunology Volume 95, Issue 6, Pages 1172-1178 (June 1995) DOI: 10.1016/S0091-6749(95)70073-0 Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 1 FEV 1 at baseline and after 4 weeks of treatment for QD and QID groups. Both groups demonstrate significant improvement after inhaled steroid therapy. Between groups there are no significant differences at baseline or after 4 weeks of treatment. Journal of Allergy and Clinical Immunology 1995 95, 1172-1178DOI: (10.1016/S0091-6749(95)70073-0) Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 2 Morning (AM) PEFR is shown at baseline and after 4 weeks of treatment for QD and QID groups. Both groups demonstrate significant improvement after inhaled steroid therapy. Between groups there are no significant differences at baseline or after 4 weeks of treatment. Journal of Allergy and Clinical Immunology 1995 95, 1172-1178DOI: (10.1016/S0091-6749(95)70073-0) Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 3 Evening (PM) PEFR is shown at baseline and after 4 weeks of treatment for QD and QID groups. Both groups demonstrate significant improvement after inhaled steroid therapy. Between groups there are no significant differences at baseline or after 4 weeks of treatment. Journal of Allergy and Clinical Immunology 1995 95, 1172-1178DOI: (10.1016/S0091-6749(95)70073-0) Copyright © 1995 Mosby, Inc. Terms and Conditions

FIG. 4 The improvement in morning (AM) PEFR and evening (PM) PEFR is compared for the QD and QID groups. The improvement in morning PEFR was similar for each treatment group. There was a trend toward more improvement in evening PEFR for the QD group compared with the QID group. Journal of Allergy and Clinical Immunology 1995 95, 1172-1178DOI: (10.1016/S0091-6749(95)70073-0) Copyright © 1995 Mosby, Inc. Terms and Conditions