Suraneni et al, table S7: Representative genes commonly upregulated in young transgenic (fl26y and svb9y) and old wt (wto) VPs compared to young wt (wty)

Slides:



Advertisements
Similar presentations
Input IgG -LSD1 -HDAC1 Untreated SAHA LSD1 HDAC1 Input IgG -LSD1 -HDAC1 IP: (IB) Figure S1 Huang, Yi et al.
Advertisements

DNA Chip Scanning DNA Chips are scanned with a laser to excite the fluorescein dye that is attached to the target cDNA. Only those probe spots where target.
Notch1 Transmembrane Receptor Oncogene. What is Notch1?  Transmembrane protein involved in a conserved and simple signaling pathway.
MDM2: Oncogene Chan Lee. Discovery of MDM2: starting with tumor suppressor p53.
Signal Pathways in Eukaryotic Cells Overview. Lipid Soluble Hormones.
Functions Receptors Signaling Chapter 11
IGF in circulation The majority (> 75 %) exists as bound form –IGF binding proteins (IGFBPs) IGFBPs –6 proteins and several related proteins –Serum IGFBP.
AP Biology Control of Eukaryotic Genes.
Historical Landmarks in Our Understanding of Proteins 1838The name "protein" (from the Greek proteios, "primary") was suggested by Berzelius for the complex.
A b Cell Cycle c Proliferation KINASE A ANCHOR PROTEIN CASPASE 3, APOPTOSIS-RELATED CYSTEINE PROTEASE NUCLEAR RECEPTOR SUBFAMILY 3, GROUP C, MEMBER 1 BRUTON’S.
Adiponectin versus angiotensin II: Key pathological role of their misbalance.
Potential therapeutic target & predictive biomarker Oncogenic IGFBP2 Sonya Song ( 宋韦 ) Beijing Shijitan Hospital Department of Oncology The Capital Medical.
Supplemental Figure 1 A B panobinostat.
NC-1 NC-2 NC-3 NC-4 NC-5 NC-6 NC-7 NC-8 NC-9 NC-10 NC-11 IN-1 IN-2 IN-3 IN-4 IN-5 IN-7 IN-8 IN-11 IN-12 IN-14 IN-16 AS-1 AS-7 AS-20 AS-21 AS-29 AS-32 AS-33.
Supplementary table 2. Genes upregulated in both microarray and RNA-seq analysis Gene IDGene SymbolGenBank accesion no.Microarray FCP.ValueRNA-seq FCTM/SP.
Table S10. A set of 140 Genes differentiating DF vs DHF (HG-U133 plus2 platform) Probeset IDGene SymbolGene Title p-value(DF vs. DHF) Fold- Change(DF vs.
・Salt responsive genes ・AP2/ERF TFs ・ABA signaling ・AP2/ERF TFs
GENES ASSOCIATED WITH CHOLESTEROL ACCUMULATION IN MACROPHAGES (TRANSCRIPTOME ANALYSIS) Nikiforov NG1,2,8, Zhelankin AV1,2, Bukrinsky M3, Makeev VJ4, Foxx.
Epidermal growth factor receptor tyrosine kinase inhibitors as initial therapy for non- small cell lung cancer: Focus on epidermal growth factor receptor.
Table 1. Genes with strong association for celiac disease
Unrooted phylogenetic tree showing the relationship between the human SLC2A gene family for all 14 members created using PHYLIP 3.6 softwareDistance between.
Inducing Angiogenesis
Supplementary Table. Gene expression profiling reveals a decrease in NFkB-driven gene signature pattern upon treatment with MLN4924. Gene ID Name Treated/
KG-501 suppresses NSCLC/IL-1β CM–induced migration of HUVECs by regulating IL-1β–induced CXC chemokine gene expression in NSCLC cells. KG-501 suppresses.
Inducing Angiogenesis
Cell Communication.
Cell Signaling.
The Cbl Family and Other Ubiquitin Ligases
Supplementary Figure 1: NVR can induce core protein assembly into capsid-like structures in vitro and inhibits HBV replication in HepG cells.
PI3K Regulatory Subunits Lose Control in Cancer
Relationship between Genotype and Phenotype
Figure 5 Classification of immunotherapies
Eukaryote Regulation and Gene Expression
Figure 1 A schematic representation of the HER2 signalling pathway
Relationship between Genotype and Phenotype
دکتر مجیری داروساز متخصص فارماکولوژی
*** *** Supplemental figure NR4As/ cyclophilin mRNA 0.6
IL-21 induces the expression of CX3CL1 in the muscle in EAM
Axl Receptor Axis: A New Therapeutic Target in Lung Cancer
Schematic view of Trk receptors signalling, showing the three major pathways involved in cell differentiation and survival. Schematic view of Trk receptors.
GPCR and heterotrimeric G-protein signalling.
Crystal Aguh, MD, Yemisi Dina, BS, C
Prospects for Riboswitch Discovery and Analysis
Transport receptors bind directly to SRP19 in a RanGTP-regulated manner. Transport receptors bind directly to SRP19 in a RanGTP-regulated manner. A GST-SRP19.
From ER to Eph Receptors: New Roles for VAP Fragments
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
Chapter 18 GABA Copyright © 2012, American Society for Neurochemistry. Published by Elsevier Inc. All rights reserved.
Alan B Sachs, Peter Sarnow, Matthias W Hentze  Cell 
Schematic representation of signaling by MCV large T antigen (T-Ag) and small t antigen (t-Ag). Schematic representation of signaling by MCV large T antigen.
Inflammatory stimuli increase angiopoietin-like protein 4 (ANGPTL4) gene and protein expression in human macrophages. Inflammatory stimuli increase angiopoietin-like.
Full-length AdIGFBP-5 and T47D cell-derived IGFBP-5 analyzed by mass spectrometry.a, intact AdIGFBP-5 was analyzed by ESI-MS. Full-length AdIGFBP-5 and.
Cell-mediated immunity Regulation of the immune response
Platelet-derived growth factor (PDGF) signalling pathway.
Function introduction to G proteins (more details in another lecture)
Fig. 1. Summary of AERD associated single nucleotide polymorphisms in the genes of immune response and arachidonate pathway. OR, odds ratio; Ref, reference.
Fig. 3 Conditionally expressed CAR using Notch as a signal induction and response pathway system. Conditionally expressed CAR using Notch as a signal induction.
Allen R. Buskirk, David R. Liu  Chemistry & Biology 
Relationship between Genotype and Phenotype
Laurel A. Grisanti et al. BTS 2018;3:
Precision autophagy. Precision autophagy. (A) Precision autophagy is a receptor-regulator-based form of autophagy. A receptor-regulator protein (such as.
Enrichment of KEGG pathways in microbial genes in different samples.
Transcriptomic changes in strains PAK and PAKpmrB6 in response to polymyxin B (PMB). Transcriptomic changes in strains PAK and PAKpmrB6 in response to.
Nat. Rev. Endocrinol. doi: /nrendo
Bortezomib induces an NRF2 signature and NRF2 protein in tumor cells from leukemic MCL. Gene sets regulated by bortezomib (Supplementary Tables S3 and.
Expression of chemokine receptors in A-498 cell line.
Rapid nucleotide exchange allows irreversible interactions between GDP-bound KRASG12C (middle) and ARS-853 (right). Rapid nucleotide exchange allows irreversible.
The Cbl Family and Other Ubiquitin Ligases
Figure 1 Analysis of CNVs of LMNB1 and its upstream region
Regulation of signaling by wild-type and oncogenic Ras.
Model of the change in receptor structure on engagement of the ligand IFN-γ. Model of the change in receptor structure on engagement of the ligand IFN-γ.
Presentation transcript:

Suraneni et al, table S7: Representative genes commonly upregulated in young transgenic (fl26y and svb9y) and old wt (wto) VPs compared to young wt (wty) VPs wto(vs)wty fl26y(vs)wty svb9y(vs)wty in wto: 200 genes ≥2 fold in fl26y: 200 genes ≥1.7 fold; in svb9y: only 51 genes ≥1.5 fold Gene Fold Gene Fold Gene Fold Ski (Sloan-Kettering viral oncogene) 10.4 Ski 12.4 Ang 3 (angiogenin 3) 5.8 Ang 3 3.8 Ang 4 5.1, 5.1 Ang 4 3.3, 2.6 Ang 1 5.1 Ang 1 3.2 Ang 2 3.4 Ang 2 2.6 Angptl4 (angiopoietin-like 4) 1.7 Angptl4 1.7 Agtrap (angiotensin II, type I 1.6 Agtr1 1.4,1.3 receptor associated protein) (angiotensin receptor 1) Usp30 (ubiquitin-specific protease 30) 4.5 Usp30 9.6 Aldh8a1 (aldehyde dehydrogenase 3.2 Aldh8a1 2.8 Aldh8a 1.8 8 family, member A1) Gab3 (growth factor receptor bound 3.0 Gab3 7.2 protein 2-associated protein 3) Gnao1 (GTP-binding protein 3.0 Gnao1 6.5 alpha subunit) Pik3c2g (PI3K, C2 domain 2.8 Pik3c2g 1.7 containing,  polypeptide) Plxna1 (Plexin A1) 2.8 Plxna1 3.3 Plxna1 1.7 Saa2 (serum amyloid A 2) 2.6, 2.0 Saa2 2.9,2.5 Saa2 1.5, 1.5 Saa1 2.0 Saa1 2.7 Saa1 1.3 Psca (prostate stem cell antigen) 2.3 Psca 3.2 Slc25a17 2.2 Slc25a17 2.1, 1.7 Slc4a1 2.2 Slc4a1 4.4 Cxcl14 (chemokine ligand 14) 1.9 Cxcl14 1.4 Rkhd1 (ring finger (C3HC4 type) 2.1 Rkhd1 3.6 Rkhd1 1.7 and KH domain containing 1) Fxyd4 (FXYD domain-containing ion 2.0 Fxyd 3.8 transport regulator 4) Eif4e (eukaryotic translation 1.6 Eif4el3 2.0 initiation factor 4E) Igfbp6 1.6 Igfbp6 1.3 Shown are some representative genes COMMONLY upregulated in wto and/or fl26y and/or svb9y compared to wty VPs. Gene names and fold increase are indicated. Some genes showed upregulation on several probesets. Genes marked in red are commonly upregulated in all 3 sets of comparisons.