From: Adenovirus Type 37 Keratitis in the C57BL/6J Mouse

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From: Adenovirus Type 37 Keratitis in the C57BL/6J Mouse Invest. Ophthalmol. Vis. Sci.. 2007;48(2):781-788. doi:10.1167/iovs.06-1036 Figure Legend: mRNA expression (A) of viral genes in mouse corneas injected with 105 TCID of Ad37 at 4 hours, 1 day, and 4 days after injection. Total RNA was isolated and viral mRNA expression analyzed by real-time PCR. Adenovirus early genes E1A 10S and E1B 19k show highest expression at 4 hours after injection, dropping sharply by day 4. The data shown represent the mean ± SD of results in two separate experiments (n = 3/timepoint). (B) Ad37 (105 TCID) was injected into each mouse cornea and viral replication was analyzed for corneas harvested immediately after injection and daily thereafter for 4 days. The viral titer dropped to 103 TCID by 4 days after injection. The values shown represent the mean ± SD of viral titers (n = 4/timepoint). Date of download: 1/2/2018 The Association for Research in Vision and Ophthalmology Copyright © 2018. All rights reserved.