The Cytoskeleton الهيكل الخلوي

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Presentation transcript:

The Cytoskeleton الهيكل الخلوي Microtubules and microfilaments The Cytoskeleton الهيكل الخلوي A network of fibres شبكة من الالياف that provide structural support تدعيم to the cell. The cytoskeleton also functions in cell motility تحرك الخلية and regulation. It is made up of 3 types of fibers Microfilaments Microtubules Intermediate filaments It has 3 main functions: Provides mechanical support of the cell and keeps organelles in their fixed locations. Helps move materials within the cell Plays a major role in cell motility

Cytoskeleton Microfilaments

Cytoskeleton سميكة رفيعة متوسطة Microfilaments Intermediate filaments Microtubules أنيبيبات دقيقة ألياف دقيقة ألياف متوسطة Thick Thin Middle سميكة رفيعة متوسطة Responsible for cell motility, and separation of chromosomes during cell division. (Tubulin protein) Support cell motility and transport materials within the cell. (Actin protein) Reinforcing the cell shape and fixing position of organelles. (Fibrous protein)

The cytoskeleton is dynamic, dismantling يتفككin one part and reassembling يتجمعin another to change cell shape. The cytoskeleton also plays a major role in cell motility حركة الخلية by interacting with motor proteins. البروتين الحركي. Motor proteins are able to move along the surface of a suitable substrate (powered by ATP). Motor proteins are the driving force behind most active transport of proteins and vesicles in the cytoplasm Cell Movement Crawling is accomplished via actin filaments and the protein myosin. In cilia and flagella motor proteins pull components of the cytoskeleton past each otherعكس بعضهم . This is also true in muscle cells.

Motor proteins Motor proteins are a class of molecular motors that are able to move along the surface of a suitable substrate. They are powered by the hydrolysis of ATP and convert chemical energy into mechanical work. Transport vesicle Motor proteins Microtubule ATP ADP+Pi MOTOR PROTEINS "WALKS" ALONG A MICROTUBULE TRACK

Interactions of motor proteins and the cytoskeleton circulates materials within the cell. The cytoskeleton may transmit mechanical signals that rearrange the nucleoli and other structures. Motor molecules also carry vesicles or organelles to various destinations إلى أماكن مختلفة provided by the cytoskeleton.

Microtubule Organelle P Motor Protein P Energy Microtubules functions as tracks قضيب that guide motor proteins carrying organelles to their destination المكان المستهدف. They move chromosomes during cell division