RESEARCH & INNOVATION SHOWCASE Dr Marie M Phelan Metabolomics is an emergent technique to profile metabolites of given biomaterial to diagnose or understand underlying cellular state Sited in the NMR Centre for Structural Biology Work both Academic and Industrial partners Professor Lu-Yun Lian Chair of Structural Biology & Director of the NMR Centre for Structural Biology Dr Marie Phelan NMR Technologist & Shared Research Facility Manager for NMR metabolomics T: +44 (0)151 795 4458 E: Lu-Yun.Lian@Liverpool.ac.uk T: +44 (0)151 795 4398 E: Marie.Phelan@Liverpool.ac.uk Poster X2

RESEARCH & INNOVATION SHOWCASE Dr Marie M Phelan University of Liverpool NMR metabolomics facility has optimised a range of biofluids and biomaterials in projects: 1. Direct-from Clinic samples research metabolite biomarkers/profiles in ◦ Blood plasma ◦ Synovial fluid ◦ Urine ◦ Peritoneal fluid 2. Postmortem for model building ◦ Cerebrospinal Fluid ◦ Cartilage ◦ Aortic tissue 3. Lab grown cells/models for in vitro drug testing or model building ◦ Parasites: Plasmodium ◦ Bacteria: Pseudomonas ◦ Human neuronal cells ◦ Evolutionary model: Daphnia Poster X2

RESEARCH & INNOVATION SHOWCASE Dr Marie M Phelan Our dedicated staff, analytical expertise and state-of-the-art equipment enable us to work with may different projects in both diagnostics and therapeutics. We work flexibly: Industrial partnerships Collaborations Apprenticeships Method development Direct machine access Pay-per-sample service Analytics and Dissemination Poster X2