From: Ultrahigh-Resolution Measurement by Optical Coherence Tomography of Dynamic Tear Film Changes on Contact Lenses Invest. Ophthalmol. Vis. Sci.. 2010;51(4):1988-1993.

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From: Ultrahigh-Resolution Measurement by Optical Coherence Tomography of Dynamic Tear Film Changes on Contact Lenses Invest. Ophthalmol. Vis. Sci.. 2010;51(4):1988-1993. doi:10.1167/iovs.09-4389 Figure Legend: Changes in PLTF and PoLTF after lens insertion. (A) 1 drop (35 μL) of artificial tears was placed on the concave surface of the lens before insertion. The PLTF and PoLTF were immediately increased compared with the precorneal tear film (PCTF, post hoc tests, P < 0.05). The PoLTF decreased continuously for the next 8 minutes (post hoc test, P < 0.05), and the PLTF decreased in a similar fashion (P < 0.05). (B) After lens insertion without prior application of a drop of artificial tears to the concave surface, the PLTF was immediately thicker than the PCTF at baseline (P < 0.05). However, the PoLTF was not different from the PCTF (P > 0.05). After 3 minutes of lens wear, both the PLTF and PoLTF decreased significantly compared with the moment of lens insertion (P < 0.05). When 35 μL artificial tears was instilled on the lens, the PLTF increased significantly and then decreased gradually in the following 8 minutes (P < 0.05). However, the PoLTF did not increase immediately after drop instillation and also did not change in the following 10 minutes (Re-ANOVA, P > 0.05). Date of download: 1/8/2018 The Association for Research in Vision and Ophthalmology Copyright © 2018. All rights reserved.