Is Anti-Hepatitis C Virus Antibody Level an Appropriate Marker to Preclude the Need for Supplemental Testing? Intervirology 2015;58:310-317 - DOI:10.1159/000441474.

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Is Anti-Hepatitis C Virus Antibody Level an Appropriate Marker to Preclude the Need for Supplemental Testing? Intervirology 2015;58:310-317 - DOI:10.1159/000441474 Fig. 1. RT-PCR test ROC curve based on different CIA cutoff levels for anti-HCV antibody detection. The area under the curve is 0.812 (95% CI: 0.783-0.841). © 2016 S. Karger AG, Basel

Is Anti-Hepatitis C Virus Antibody Level an Appropriate Marker to Preclude the Need for Supplemental Testing? Intervirology 2015;58:310-317 - DOI:10.1159/000441474 Fig. 2. RIBA test ROC curve based on different CIA cutoff levels for anti-HCV antibody detection. The area under the curve is 0.932 (95% CI: 0.916-0.948). © 2016 S. Karger AG, Basel

Is Anti-Hepatitis C Virus Antibody Level an Appropriate Marker to Preclude the Need for Supplemental Testing? Intervirology 2015;58:310-317 - DOI:10.1159/000441474 Fig. 3. RIBA results relative to S/Co ratios according to antibody level. Samples with an S/Co ratio ≥20, between 3.0 and 19.99, or between 1.0 and 2.99 were classified as high antibody levels, low antibody levels, or very low antibody levels, respectively. These antibody levels are outlined in parentheses below each bar. The percentages of RIBA-positive samples according to these antibody levels were as follows: high antibody levels, 98.3% (404/411); low antibody levels, 6.0% (128/213), and very low antibody levels, 16.2% (45/277). IND = Indeterminate; N = negative; P = positive. © 2016 S. Karger AG, Basel

Is Anti-Hepatitis C Virus Antibody Level an Appropriate Marker to Preclude the Need for Supplemental Testing? Intervirology 2015;58:310-317 - DOI:10.1159/000441474 Fig. 4. Distribution of HCV viremic samples according to antibody level. Samples with an S/Co ratio ≥20, between 3.0 and 19.99, or between 1.0 and 2.99 were classified as high antibody levels, low antibody levels, or very low antibody levels, respectively. The percentages of HCV viremic samples according to these antibody levels were as follows: high antibody levels, 91.4% (374/409); low antibody levels, 55.4% (113/204), and very low antibody levels, 36.0% (99/275). These antibody levels are outlined in parentheses below each bar. Because of insufficient sample volume, 2 samples with high antibody levels, 9 samples with low antibody levels, and 2 samples with very low antibody levels were not tested for HCV RNA. © 2016 S. Karger AG, Basel