Tuesday, Jan. 12 A Day Wednesday 8AM sharp meet in Stuber Gym Sharpened Pencils, ID & Calculator ACT Science Advice Questions over experiments? Quiz: DNA Structure Notes- History of DNA

Discovery of DNA A Brief History

Friedrich Meisher 1871 Used old wound wrappings to take pus samples From the samples, he isolated and extracted DNA Experiment documented gone unnoticed for many years

Phoebus Levene 1910 Determined that DNA contains 3 parts: nitrogenous bases (adenine, thymine, guanine and cytosine) Phosphate Deoxyribose Sugar

Erwin Chargaff 1949 Virus pieX174- single stranded DNA molecule

Erwin Chargaff 1949 Determined that the amounts of A=T and the amounts of G=C Discovered complementary base pairing Did not respect Watson and Crick as scientists

Rosalind Franklin 1950s X- ray diffraction to determine double helix structure of DNA Calculated the dimensions of a DNA molecule

Maurice Wilkins Worked with Rosalind Franklin Showed Francis Crick and James Watson the x- ray diffraction of DNA DID NOT GAIN PERMISSION from Franklin

Watson and Crick 1953 Used information from Levene, Chargaff and Franklin (among others) Built a model of the structure of DNA Wrote a paper regarding their findings Made hypothesis for DNA replication

Protein (Histones)