Tuesday, Jan. 12 A Day Wednesday 8AM sharp meet in Stuber Gym Sharpened Pencils, ID & Calculator ACT Science Advice Questions over experiments? Quiz: DNA Structure Notes- History of DNA
Discovery of DNA A Brief History
Friedrich Meisher 1871 Used old wound wrappings to take pus samples From the samples, he isolated and extracted DNA Experiment documented gone unnoticed for many years
Phoebus Levene 1910 Determined that DNA contains 3 parts: nitrogenous bases (adenine, thymine, guanine and cytosine) Phosphate Deoxyribose Sugar
Erwin Chargaff 1949 Virus pieX174- single stranded DNA molecule
Erwin Chargaff 1949 Determined that the amounts of A=T and the amounts of G=C Discovered complementary base pairing Did not respect Watson and Crick as scientists
Rosalind Franklin 1950s X- ray diffraction to determine double helix structure of DNA Calculated the dimensions of a DNA molecule
Maurice Wilkins Worked with Rosalind Franklin Showed Francis Crick and James Watson the x- ray diffraction of DNA DID NOT GAIN PERMISSION from Franklin
Watson and Crick 1953 Used information from Levene, Chargaff and Franklin (among others) Built a model of the structure of DNA Wrote a paper regarding their findings Made hypothesis for DNA replication
Protein (Histones)