Clinical practice in Crohn's disease in bordering regions of two countries: Different medical options, distinct surgical events  Fernando Magro, Manuel.

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Clinical practice in Crohn's disease in bordering regions of two countries: Different medical options, distinct surgical events  Fernando Magro, Manuel Barreiro-de Acosta, Paula Lago, Daniel Carpio, José Cotter, Ana Echarri, Raquel Gonçalves, Santos Pereira, Laura Carvalho, Aurelio Lorenzo, Luisa Barros, Javier Castro, Jorge Amil Dias, Susana Rodrigues, Francisco Portela, Camila Dias, Altamiro da Costa-Pereira  Journal of Crohn's and Colitis  Volume 4, Issue 3, Pages 301-311 (September 2010) DOI: 10.1016/j.crohns.2009.12.004 Copyright © 2009 European Crohn's and Colitis Organisation Terms and Conditions

Figure 1 Distribution of the Northern Portuguese and Galician CD populations by age at diagnosis (A), location (B) and behavior (C) according to treatment — classified in six disease severity categories (modified of Silverstein et al.19 classification). Score 1 was reserved for mild disease (without steroids, immunosuppressants, biologic treatment or surgery at any given year of disease), score 2 for moderate disease (patients treated with corticosteroids requiring a dose of prednisolone above 10mg/day or two or more steroid treatments within a period of six months), score 3 for severe disease (patients treated with immunosuppressants without biologic treatment or surgery), score 4 for severe refractory disease (patients treated with immunosuppressants and biologic treatment without surgery), score 5 for surgically treated disease (patients without immunosuppressants or biologic treatment) and finally score 6 for severe refractory disease who came to need surgery as well as immunosuppressants and biologic treatment. Journal of Crohn's and Colitis 2010 4, 301-311DOI: (10.1016/j.crohns.2009.12.004) Copyright © 2009 European Crohn's and Colitis Organisation Terms and Conditions

Figure 2 Delta of surgical intervention procedures related with CD in the Northern Portuguese and Galician CD population allocated by age at diagnosis (A), Location (B) and behavior (C). Journal of Crohn's and Colitis 2010 4, 301-311DOI: (10.1016/j.crohns.2009.12.004) Copyright © 2009 European Crohn's and Colitis Organisation Terms and Conditions