DLPFC Semi-automatic Segmentor: With minimal user interaction, this rule-based algorithm will segment the DLPFC from an input volume. This is a Slicer project but may have components that are appropriate for ITK. Team Plan/Expected Challenges Ramsey Al-Hakim, GT (algorithms) (contact) John Melonakos (algorithms) Alex Yarmakovich, Isomics (software) Jim Fallon, UCI (clinical) Algorithms: start with the Matlab implementation and port to Slicer then explore porting to ITK. Software: computational speed. Intuitive user interface. Clinical: Validation of results. Accomplished by end of Programming Week Build Slicer user interface. Final Step: Wrap ITK Bayesian Classifier Filter in VTK, and add to module.