Comparison of Telomerase Activity and Matrix Metalloproteinase-9 in Voided Urine and Bladder Wash Samples as a Useful Diagnostic Tool for Bladder Cancer

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Comparison of Telomerase Activity and Matrix Metalloproteinase-9 in Voided Urine and Bladder Wash Samples as a Useful Diagnostic Tool for Bladder Cancer Sanaa Eissa, Randa A Labib, M.Sherif Mourad, Khaled Kamel, O El-Ahmady European Urology Volume 44, Issue 6, Pages 687-694 (December 2003) DOI: 10.1016/S0302-2838(03)00417-2

Fig. 1 Telomerase activity in voided urine and bladder wash as well as MMP-9 activity (ng/ml) in voided urine (normalized/0.1μg creatinine) in different investigated groups. European Urology 2003 44, 687-694DOI: (10.1016/S0302-2838(03)00417-2)

Fig. 2 Voided urine cytology showing squamous cell carcinoma. There is exfoliation of numerous cancer cells as single cells and in sheet with prominent cellular and nuclear polymorphism with tumor diathesis background (Pap×250). European Urology 2003 44, 687-694DOI: (10.1016/S0302-2838(03)00417-2)

Fig. 3 Bladder cytology showing papillary transitional cell carcinoma. Note a papillary arrangement with tails. There is three-dimensional clusters showing marked nuclear enlargement with disorderly arranged and coarse clumping chromatin (Pap×250). European Urology 2003 44, 687-694DOI: (10.1016/S0302-2838(03)00417-2)