Invest. Ophthalmol. Vis. Sci ;55(7): doi: /iovs Figure Legend:

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From: Decreased Proteasomal Activity Causes Photoreceptor Degeneration in Mice Invest. Ophthalmol. Vis. Sci.. 2014;55(7):4682-4690. doi:10.1167/iovs.13-13272 Figure Legend: Photoreceptor cell degeneration caused by proteasome dysfunction. (A) Representative images of retinal sections stained with HE from WT mice and β5t-Tg mice at 1, 3, 6, and 9 months of age. Scale bar: 10 μm. (B) Quantification analysis of INL and ONL thickness (n = 3–8). Closed circles indicate WT mice, and open circles indicate β5t-Tg mice. (C) Outer nuclear layer/INL ratio (n = 3–8). (D) Outer segment/INL ratio (n = 3–7). (E) Ultrastructure of OS at 6 months of age. Scale bar: 2 μm. Values are mean ± SEM. *P < 0.05; **P < 0.01. Date of download: 3/1/2018 The Association for Research in Vision and Ophthalmology Copyright © 2018. All rights reserved.