Supplement 1. This patient's horizontal magnetic resonance scan (left) and matched Talairach-Tournoux atlas image (right). Arrows show approximate areas of hemorrhage and infarction (+24, 6, A, a, and +20, 6-7, A, a, and +18, 6-7, AB, a). Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain. New York: Thieme; 1988. Used with permission.

Supplement 2. This patient's sagittal T1-weighted magnetic resonance image of hemorrhage (left) and matched Talairach-Tournoux atlas image (right). The arrows point to Brodmann area 10. Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain. New York: Thieme; 1988. Used with permission.

Supplement 3. This patient's magnetic resonance gradient echo sequence (A) and diffusion-weighted sequence (B), showing the discrete mesial frontopolar hemorrhage with minor ischemia and infarction on the right. Lesion volume = 2.3 cm3. B A

Supplement 4. This patient's magnetic resonance FLAIR (left) and perfusion (right) images, showing no regional hypoperfusion, diaschisis, or other concomitant abnormality.

Supplement 5. Frontopolar cortex sub-region activation patterns (regional cerebral blood flow and blood oxygen level-dependent). MLT indicates multitasking; MNT, mentalizing; and EP, episodic memory. Adapted from Gilbert SJ et al. J Cogn Neurosci 2006;18:932 and from Dumontheil I et al. Dev Med Child Neurol 2008;50:168. MLT EP EP MNT