Patient emotions and perceptions of antiepileptic drug changes and titration during treatment for epilepsy  Jesse Fishman, Greg Cohen, Colin Josephson, Ann Marie Collier, Srikanth Bharatham, Ying Zhang, Imane Wild  Epilepsy & Behavior  Volume 69, Pages 44-52 (April 2017) DOI: 10.1016/j.yebeh.2017.01.032 Copyright © 2017 Ellen Carey, UCB Brussels, Belgium Terms and Conditions

Fig. 1 Valence of primary emotions associated with an antiepileptic drug regimen change, by duration of change (N=345). Epilepsy & Behavior 2017 69, 44-52DOI: (10.1016/j.yebeh.2017.01.032) Copyright © 2017 Ellen Carey, UCB Brussels, Belgium Terms and Conditions

Fig. 2 Basic emotion groups (from combined primary emotions) associated with antiepileptic drug change, by duration of regimen change for the overall population (N=345). Epilepsy & Behavior 2017 69, 44-52DOI: (10.1016/j.yebeh.2017.01.032) Copyright © 2017 Ellen Carey, UCB Brussels, Belgium Terms and Conditions

Fig. 3 Basic emotion groups (from combined primary emotions) associated with antiepileptic drug (AED) change, by type of medication change (N=345). Epilepsy & Behavior 2017 69, 44-52DOI: (10.1016/j.yebeh.2017.01.032) Copyright © 2017 Ellen Carey, UCB Brussels, Belgium Terms and Conditions

Fig. 4 Basic emotion groups (from combined primary emotions) associated with antiepileptic drug (AED) change, by the number of concomitant AEDs (N=345). Epilepsy & Behavior 2017 69, 44-52DOI: (10.1016/j.yebeh.2017.01.032) Copyright © 2017 Ellen Carey, UCB Brussels, Belgium Terms and Conditions

Fig. 5 Emotion categories (positive vs. negative) associated with antiepileptic drug (AED) monotherapy (N=73), by type of AED: (A) SCB(+) or SCB(−) AED category, (B) AED with versus without mood-stabilizing properties. SCB(+): sodium-channel blocking AED; carbamazepine, lamotrigine, lacosamide, oxcarbazepine, phenytoin. SCB(−): non–sodium-channel blocking AED; levetiracetam, perampanel, topiramate, divalproex. AEDs with mood-stabilizing properties were those approved by the US Food and Drug Administration for the treatment of bipolar disorder (carbamazepine, lamotrigine, sodium valproate). Epilepsy & Behavior 2017 69, 44-52DOI: (10.1016/j.yebeh.2017.01.032) Copyright © 2017 Ellen Carey, UCB Brussels, Belgium Terms and Conditions